Coroneos Christopher J, Voineskos Sophocles H, Christakis Marie K, Thoma Achilleas, Bain James R, Brouwers Melissa C
Division of Plastic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.
BMJ Open. 2017 Jan 27;7(1):e014141. doi: 10.1136/bmjopen-2016-014141.
The objective of this study was to establish an evidence-based clinical practice guideline for the primary management of obstetrical brachial plexus injury (OBPI). This clinical practice guideline addresses 4 existing gaps: (1) historic poor use of evidence, (2) timing of referral to multidisciplinary care, (3) Indications and timing of operative nerve repair and (4) distribution of expertise.
The guideline is intended for all healthcare providers treating infants and children, and all specialists treating upper extremity injuries.
The evidence interpretation and recommendation consensus team (Canadian OBPI Working Group) was composed of clinicians representing each of Canada's 10 multidisciplinary centres.
An electronic modified Delphi approach was used for consensus, with agreement criteria defined a priori. Quality indicators for referral to a multidisciplinary centre were established by consensus. An original meta-analysis of primary nerve repair and review of Canadian epidemiology and burden were previously completed.
7 recommendations address clinical gaps and guide identification, referral, treatment and outcome assessment: (1) physically examine for OBPI in newborns with arm asymmetry or risk factors; (2) refer newborns with OBPI to a multidisciplinary centre by 1 month; (3) provide pregnancy/birth history and physical examination findings at birth; (4) multidisciplinary centres should include a therapist and peripheral nerve surgeon experienced with OBPI; (5) physical therapy should be advised by a multidisciplinary team; (6) microsurgical nerve repair is indicated in root avulsion and other OBPI meeting centre operative criteria; (7) the common data set includes the Narakas classification, limb length, Active Movement Scale (AMS) and Brachial Plexus Outcome Measure (BPOM) 2 years after birth/surgery.
The process established a new network of opinion leaders and researchers for further guideline development and multicentre research. A structured referral form is available for primary care, including referral recommendations.
本研究的目的是制定一项基于证据的产科臂丛神经损伤(OBPI)初级管理临床实践指南。该临床实践指南解决了4个现存差距:(1)以往对证据的利用不足;(2)多学科护理转诊时机;(3)手术神经修复的指征和时机;(4)专业知识的分布。
本指南适用于所有治疗婴幼儿的医疗服务提供者以及所有治疗上肢损伤的专科医生。
证据解读与推荐共识团队(加拿大OBPI工作组)由代表加拿大10个多学科中心的临床医生组成。
采用电子改良德尔菲法达成共识,事先定义了一致标准。通过共识确定了转诊至多学科中心的质量指标。此前已完成对初级神经修复的原始荟萃分析以及加拿大流行病学和负担的综述。
7项建议针对临床差距,指导识别、转诊、治疗和结局评估:(1)对有手臂不对称或危险因素的新生儿进行OBPI体格检查;(2)在1个月内将患有OBPI的新生儿转诊至多学科中心;(3)提供出生时的妊娠/分娩史和体格检查结果;(4)多学科中心应包括一名有OBPI治疗经验的治疗师和周围神经外科医生;(5)应由多学科团队建议进行物理治疗;(6)对于神经根撕脱和其他符合中心手术标准的OBPI,建议进行显微外科神经修复;(7)通用数据集包括出生/手术后2年的纳拉卡斯分类、肢体长度、主动运动量表(AMS)和臂丛神经结局测量(BPOM)。
该过程建立了一个新的意见领袖和研究人员网络,以进一步制定指南和开展多中心研究。提供了一份结构化转诊表用于初级保健,包括转诊建议。