Ueta Koji, Yamashita Kimihiro, Sumi Yasuo, Kanemitsu Kiyonori, Yamamoto Masashi, Kanaji Shingo, Oshikiri Taro, Nakamura Tetsu, Suzuki Satoshi, Kakeji Yoshihiro
Division of Gastrointestinal Surgery, Kobe University Graduate School of Medicine.
Gan To Kagaku Ryoho. 2016 Nov;43(12):1443-1445.
No consensus has been reached with regard to the optimal treatment strategy and the prognosis of patients with advanced rectal cancer and inguinal lymph node metastasis. We, therefore, retrospectively analyzed the outcomes of 41 patients with locally advanced rectal cancer who underwent surgery after neoadjuvant chemoradiotherapy(NACRT). Six patients, with clinical inguinal lymph node metastasis determined by pretreatment imaging, underwent inguinal lymph node dissections after NACRT. Five patients survived without a relapse. Only 1 patient, who had been diagnosed with pathological inguinal lymph node metastasis, had a relapse in the right iliac lymph node 6 years after surgery. Surgical treatment after NACRT for rectal adenocarcinoma with inguinal lymph node metastasis contributes to an improvement in outcomes. NACRT plus inguinal lymph node dissection is an effective strategy for patients with inguinal lymph node metastasis from rectal adenocarcinoma.
对于晚期直肠癌合并腹股沟淋巴结转移患者的最佳治疗策略和预后，目前尚未达成共识。因此，我们回顾性分析了41例局部晚期直肠癌患者在新辅助放化疗（NACRT）后接受手术的结果。6例经术前影像学检查确定有临床腹股沟淋巴结转移的患者，在NACRT后接受了腹股沟淋巴结清扫术。5例患者存活且无复发。只有1例被诊断为病理腹股沟淋巴结转移的患者在术后6年右侧髂淋巴结复发。NACRT后对合并腹股沟淋巴结转移的直肠腺癌进行手术治疗有助于改善预后。NACRT联合腹股沟淋巴结清扫术是治疗直肠腺癌腹股沟淋巴结转移患者的有效策略。
