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[三例成功的经尿道膀胱肿瘤切除术治疗结直肠癌膀胱复发]

[Three Successful TUR Treatments of Urinary Bladder Recurrence of Colorectal Carcinoma].

作者信息

Nishimura Yoji, Kazama Shinsuke, Nishizawa Yusuke, Ishikawa Hideki, Takano Michitoshi, Arai Shu, Takenoya Takashi, Kawashima Yoshiyuki, Kageyama Yukio, Fukui Naotaka, Sakamoto Hirohiko

机构信息

Dept. of Gastroenterological Surgery, Saitama Cancer Center.

出版信息

Gan To Kagaku Ryoho. 2016 Nov;43(12):1638-1640.

PMID:28133083
Abstract

We analyzed whether TUR was feasible in 4 cases of urinary bladder recurrence of sigmoid colon cancer that invaded into the bladder. Case No. 1 involved a 66-year-old male who presented with sigmoid colon cancer that had invaded the urinary bladder; he underwent sigmoidectomy with partial bladder resection. Six months after the operation, a small, protruded lesion in his urinary bladder was detected and TUR was performed. He has been cancer free for 10 years. Case No. 2 involved a 53- year-old female who underwent sigmoidectomy and hepatectomy for her sigmoid colon cancer and liver metastasis. She developed bladder and liver metastases, which were resected. Four months later, she underwent TUR because she developed a small recurrent tumor in the bladder. Since then, she has had no intrapelvic recurrence for 6 years. Case No. 3 was a 44- year-old male who underwent bladder-preserving resection for a sigmoid colon cancer that had invaded his bladder. He developed a relatively large bladder tumor 1 year 6 months later. TUR was performed and he was administered CRT. He has had no recurrences for 2 years 5 months. Case No. 4 was a 68-year-old male who underwent bladder-preserving surgery for a sigmoid colon cancer that had invaded his bladder. Because he developed a recurrence in the bladder, he underwent TUR 3 months later. He developed a recurrence in the bladder again 1 year 7 months later, and he underwent TUR again. Multiple organ metastases became evident and was prescribed chemotherapy for 2 years. From these cases, we conclude that TUR may be a feasible option for small, protruded recurrences in the bladder, but we should not hesitate to perform total cystectomy if the first TUR is unsuccessful.

摘要

我们分析了经尿道膀胱肿瘤切除术(TUR)对4例侵犯膀胱的乙状结肠癌膀胱复发患者是否可行。病例1为一名66岁男性,患有侵犯膀胱的乙状结肠癌;他接受了乙状结肠切除术及部分膀胱切除术。术后6个月,在其膀胱内检测到一个小的突出病变,并进行了TUR。他已无癌生存10年。病例2为一名53岁女性,因乙状结肠癌伴肝转移接受了乙状结肠切除术和肝切除术。她出现了膀胱和肝转移,均进行了切除。4个月后,因膀胱出现小的复发性肿瘤,她接受了TUR。从那时起,她盆腔内未复发已达6年。病例3是一名44岁男性,因侵犯膀胱的乙状结肠癌接受了保留膀胱的切除术。1年6个月后,他出现了一个相对较大的膀胱肿瘤。进行了TUR,并给予同步放化疗(CRT)。他已无复发2年5个月。病例4是一名68岁男性,因侵犯膀胱的乙状结肠癌接受了保留膀胱手术。由于膀胱复发,3个月后他接受了TUR。1年7个月后,他膀胱再次复发,再次接受了TUR。出现了多处器官转移,并接受了2年的化疗。从这些病例中,我们得出结论,TUR对于膀胱内小的突出复发病变可能是一种可行的选择,但如果首次TUR不成功,应毫不犹豫地进行全膀胱切除术。

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