Komagome Masahiko, Ninomiya Riki, Nakazawa Akiko, Mitsui Tetsuya, Maki Akira, Ozawa Fumiaki, Beck Yoshifumi
Dept. of Hepato-Biliary-Pancreatic Surgery, Saitama Medical Center, Saitama Medical University.
Gan To Kagaku Ryoho. 2016 Nov;43(12):1656-1658.
Unresectable(UR)pancreatic cancer often causes duodenal obstruction. Case 1: A 58-year-old man was diagnosed with UR pancreatic cancer with obstruction of the 3rd duodenal portion. A duodenum 2nd portion jejunum bypass was performed, and FOLFIRINOX was introduced and continued over 6 months. Case 2: A 74-year-old man was diagnosed with UR pancreatic cancer with obstruction of the duodenum near the Treitz ligament. A duodenum 3rd portion jejunum bypass was performed, and gemcitabine plus nab-paclitaxel was introduced. After 8 courses of GN, adjuvant surgery was performed. Both patients resumed oral intake within a few days after bypass, their performance statuses(PS)were improved, and their body weights increased. Because a duodenal jejunum bypass is more physiological than a gastro-jejunum bypass and duodenal stent, stable ingestion is enabled, and they are stable enough for early initiation of chemotherapy.
