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[吉西他滨联合顺铂化疗后手术切除治疗多发淋巴结转移的肝内胆管癌——1例报告]

[Surgical Resection after Gemcitabine plus Cisplatin Chemotherapy for Intrahepatic Cholangiocarcinoma with Multiple Lymph Node Metastases - Report of a Case].

作者信息

Otani Takahiro, Sakata Jun, Kameyama Hitoshi, Otani Ayaka, Hirose Yuki, Tamura Hiroshi, Morimoto Yuta, Miura Kohei, Yoshino Kei, Kido Tomoki, Kobayashi Takashi, Endo Kazuhiko, Wakai Toshifumi

机构信息

Dept. of Surgery, Akita Kosei Medical Center.

出版信息

Gan To Kagaku Ryoho. 2016 Nov;43(12):1764-1766.

Abstract

An 82-year-old man with upper abdominal pain was referred to our hospital because of an elevated serum CEA level and dilatation of the intrahepatic bile ducts on ultrasonography.Computed tomography revealed a hypovascular mass measuring 5.0 cm in size in the lateral section, dilatation of the peripheral intrahepatic bile ducts, and swollen lymph nodes around the lesser curvature of the stomach, the common hepatic artery, and the paraaorta.He was diagnosed with unresectable intrahepatic cholangiocarcinoma, and he received chemotherapy with biweekly gemcitabine plus cisplatin.After 33 courses of the chemotherapy, computed tomography revealed that the tumor size decreased over 63%, and all swollen lymph nodes had almost resolved.He underwent a left hemihepatectomy 1 year 6 months after the start of the chemotherapy.He remains alive and well with no evidence of recurrence, 11 months after resection.

摘要

一名82岁男性因上腹部疼痛入院,其血清癌胚抗原(CEA)水平升高,超声检查显示肝内胆管扩张。计算机断层扫描(CT)显示肝外侧段有一个大小为5.0 cm的低血运肿块,肝内周边胆管扩张,胃小弯、肝总动脉和腹主动脉旁淋巴结肿大。他被诊断为无法切除的肝内胆管癌,并接受了每两周一次的吉西他滨联合顺铂化疗。化疗33个疗程后,CT显示肿瘤大小缩小超过63%,所有肿大的淋巴结几乎完全消退。化疗开始1年6个月后,他接受了左半肝切除术。切除术后11个月,他仍然健在,无复发迹象。

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