Ueda Aiko, Yamamoto Daigo, Tsubota Yu, Sueoka Noriko, Yoshikawa Katsuhiro, Kon Masanori
Dept. of Surgery, Kansai Medical University.
Gan To Kagaku Ryoho. 2016 Nov;43(12):2252-2254.
Metastasis of peritoneal serous carcinoma to the breast and axillary lymph nodes is rare. We present a case of serous carcinoma of the peritoneum with metastases to the breast and axillary lymph nodes. A 72-year-old woman was diagnosed with Stage III peritoneal serous carcinoma in November 2009; she was treated with 6 courses of paclitaxel and carboplatin. In December 2015, she had a palpable mass(2×2 cm)and enlarged axillary lymph nodes. Mammography did not reveal any mass(C1)and ultrasonographic examination demonstrated a partially ill-defined hypoechoic mass with a diameter of 8.7× 7.1 mm. Cytological examination of the axillary lymph node revealed malignancy; breast carcinoma metastasis was suspected and the patient underwent breast-conserving surgery. Histopathological examination of the specimens(breast and axillary lymph nodes)revealed adenocarcinoma, and immunohistochemistry analysis showed that the specimens were CK7(+), CK20(-), CA125(+), PAX8(+), and GCDFP15(-). Taken together, the results indicated peritoneal serous carcinoma metastases to the breast and axillary lymph nodes.
We report a case of serous carcinoma of the peritoneum with metastases to the breast and axillary lymph nodes.
腹膜浆液性癌转移至乳腺及腋窝淋巴结较为罕见。我们报告一例腹膜浆液性癌伴乳腺及腋窝淋巴结转移的病例。一名72岁女性于2009年11月被诊断为Ⅲ期腹膜浆液性癌；她接受了6个疗程的紫杉醇和卡铂治疗。2015年12月，她可触及一个肿块（2×2厘米）且腋窝淋巴结肿大。乳腺钼靶检查未发现任何肿块（C1），超声检查显示一个直径为8.7×7.1毫米的边界部分不清的低回声肿块。腋窝淋巴结细胞学检查显示为恶性；怀疑为乳腺癌转移，患者接受了保乳手术。标本（乳腺及腋窝淋巴结）的组织病理学检查显示为腺癌，免疫组化分析表明标本CK7（+）、CK20（-）、CA125（+）、PAX8（+）、GCDFP15（-）。综合来看，结果表明为腹膜浆液性癌转移至乳腺及腋窝淋巴结。
我们报告一例腹膜浆液性癌伴乳腺及腋窝淋巴结转移的病例。
