Vieth Michael, Montgomery Elizabeth
Institute for Pathology, Klinikum Bayreuth, Preuschwitzer Str. 101, 95445, Bayreuth, Germany.
Johns Hopkins Medical Institutions, Weinberg 2242, 401 North Broadway, Baltimore, MD, 21231, USA.
Virchows Arch. 2017 Mar;470(3):245-266. doi: 10.1007/s00428-017-2077-3. Epub 2017 Jan 30.
Medication-associated gastrointestinal (GI) tract injury has been known for centuries for some medications. The more recently introduced biologicals are a class of drugs that constantly increases, and as such, the spectrum of GI tract side effects is steadily growing. This review covers not only long-known GI tract side effects of drugs but also those more recently described. A comprehensive but concise list of medications used in daily practice and associated with GI tract injury is presented.
几个世纪以来,人们已经知晓某些药物会导致与药物相关的胃肠道损伤。近年来新引入的生物制剂是一类不断增加的药物,因此,胃肠道副作用的范围也在稳步扩大。本综述不仅涵盖了药物长期以来已知的胃肠道副作用,还包括那些最近才被描述的副作用。文中列出了一份日常临床实践中使用的、与胃肠道损伤相关的药物的全面而简明的清单。