Urasyanandana K, Withayasuk P, Songsaeng D, Aurboonyawat T, Chankaew E, Churojana A
1 Phramongkutklao hospital, Phramongkutklao College of Medicine, Thailand.
2 Siriraj hospital, Mahidol University, Thailand.
Interv Neuroradiol. 2017 Jun;23(3):240-248. doi: 10.1177/1591019917691252. Epub 2017 Jan 29.
Objective Intracranial spontaneous vertebral artery dissecting aneurysms commonly occur in the third to fifth decades of life, and are mostly associated with hypertension. Patients present with intracranial haemorrhage or thromboembolic events. Patients who present with intracranial haemorrhage carry about a 70% risk of recurrent bleeding. Patients with a posterior-inferior cerebellar artery (PICA) or ipsilateral dominant vertebral artery involve selecting which parent vessel could not be sacrificed. Recent reconstructive techniques such as stent-assisted coiling embolisation and flow-diverting stents are effective treatments of choice. Methods Seventeen patients presented subarachnoid haemorrhage and nine patients with other symptoms. Sacrificing the parent vertebral artery was the first choice for surgical or endovascular methods. Endovascular reconstructive treatment by stent-assisted coiling embolisation was indicated in dissecting vertebral artery aneurysms with ipsilateral dominant vertebral artery or PICA involvement. Clinical outcomes were determined using the modified Rankin Score (mRS) at 90 days, with favourable outcomes defined as 0 to 2. Results Of the patients presenting with ruptured aneurysms, 11 (61.1%) had a good clinical outcome, with a mRS of 0-2. Favourable Hunt and Hess grading (65%), mild to moderate GCS (65%) and total occlusion of aneurysms after treatment (65%) were significantly good prognostic factors in patients with ruptured vertebral artery dissecting aneurysms. Conclusion Endovascular parent vessel sacrifice could be the first choice to treat a ruptured vertebral artery dissecting aneurysm. Stent-assisted coiling to preserve the patency of the parent artery and its branches is a promising treatment for vertebral artery dissections.
目的 颅内自发性椎动脉夹层动脉瘤常见于30至50岁人群,大多与高血压相关。患者表现为颅内出血或血栓栓塞事件。出现颅内出血的患者复发出血风险约为70%。累及小脑后下动脉(PICA)或同侧优势椎动脉的患者,在选择不能牺牲的供血动脉时存在困难。近期的重建技术,如支架辅助弹簧圈栓塞和血流导向支架,是有效的治疗选择。方法 17例患者表现为蛛网膜下腔出血,9例有其他症状。手术或血管内治疗的首选是牺牲供血椎动脉。对于累及同侧优势椎动脉或PICA的椎动脉夹层动脉瘤,采用支架辅助弹簧圈栓塞进行血管内重建治疗。使用改良Rankin量表(mRS)在90天时确定临床结局,良好结局定义为mRS为0至2。结果 在动脉瘤破裂的患者中,11例(61.1%)临床结局良好,mRS为0 - 2。Hunt和Hess分级良好(65%)、格拉斯哥昏迷量表(GCS)为轻度至中度(65%)以及治疗后动脉瘤完全闭塞(65%)是椎动脉夹层动脉瘤破裂患者显著的良好预后因素。结论 血管内牺牲供血动脉可能是治疗破裂椎动脉夹层动脉瘤的首选方法。支架辅助弹簧圈栓塞以保留供血动脉及其分支的通畅性是治疗椎动脉夹层的一种有前景的方法。