Zang Y Z, Wang Z G, Wang C W, Ding X, Wang X F, Wang L L
The Second Hospital of Shandong University, Jinan 250033, China.
Zhonghua Yi Xue Za Zhi. 2017 Jun 20;97(23):1773-1777. doi: 10.3760/cma.j.issn.0376-2491.2017.23.004.
To summarize the classifications and optimize endovascular treatment of the dissecting aneurysms of the vertebral artery (DAVA). The clinical information of 39 cases of DAVA treated with endovascular methods in our department between January 2007 and September 2016 were analyzed retrospectively.According to the location of the aneurysm in relation to the posterior inferior cerebellar artery (PICA), the aneurysms were classified into three types: type pre-PICA, located proximally to the PICA; type in-PICA, located at the PICA origin; and type post-PICA located distally to the PICA.According to the hemodynamics of the contralateral vertebral artery, the aneurysms were classified into two types: compensatory type: including well-developed contralateral vertebral arteries and a guaranteed posterior circulation blood supply following the occlusion of the ipsilateral vertebral artery; and non-compensatory type: including contralateral vertebral arteries that were hypoplastic and provided an inadequate posterior circulation blood supply following ipsilateral vertebral artery occlusion.The choices of reconstructive or destructive methods were made according to the above-mentioned classification, combined with the consideration of morphological features and onset styles.Reconstructive surgery included stent-assisted coil embolization and the placement of multiple overlapping stents (6 patients). Destructive surgery referred to coil embolization combined with proximal coil trapping of the dissected segment of the parent artery (CE+ PT). A total of 16 patients were type pre-PICA, of which 9 patients were compensatory type and 7 were non-compensatory type.In compensatory type, 4 underwent coil embolization combined with proximal coil trapping of the dissected segment of the parent artery (CE+ PT) and 5 underwent stent-assisted coil embolization (stent/coils). In non-compensatory type, 6 underwent stent/coils and 1 underwent multiple overlapping stents placement (stents). Nine patients were type in-PICA, of which 5 patients were compensatory type and 4 were non-compensatory type. In compensatory type, all patients underwent stent/coils.In non-compensatory type, 2 underwent stent/coils and 2 underwent multiple overlapping stents placement (stents). Fourteen patients were type post-PICA, of which 8 patients were compensatory type and 6 were non-compensatory type.In compensatory type, 6 underwent CE+ PT, 1 underwent stent/coils and 1 underwent stents. In non-compensatory type, 4 underwent stent/coils and 2 underwent stents.Totally, there were 10 underwent CE+ PT, 23 underwent stent/coils and 6 underwent stents.The incidence of perioperative complications was 7.7% (3/39), and the death rate associated with these complications was 5.1% (2/39). Of the 36 patients followed with long-term repeated angiographic examinations, 28(77.8%) patients had complete occlusion.Clinical outcome evaluations were performed using the Modified Rankin Scale and resulted in the following scores: 0-2 for 36 patients, 3-6 for 3 patients. The classifications based on location, hemodynamics, morphological features and onset styles of the DAVA is safe and effective for the choice of the endovascular methods.
总结椎动脉夹层动脉瘤(DAVA)的分类并优化其血管内治疗。回顾性分析2007年1月至2016年9月间我科采用血管内方法治疗的39例DAVA患者的临床资料。根据动脉瘤相对于小脑后下动脉(PICA)的位置,将动脉瘤分为三种类型:PICA前型,位于PICA近端;PICA内型,位于PICA起始处;PICA后型,位于PICA远端。根据对侧椎动脉的血流动力学情况,将动脉瘤分为两种类型:代偿型,包括对侧椎动脉发育良好且同侧椎动脉闭塞后后循环血供有保障;非代偿型,包括对侧椎动脉发育不良且同侧椎动脉闭塞后后循环血供不足。根据上述分类,结合形态学特征和发病方式,选择重建或毁损性方法。重建性手术包括支架辅助弹簧圈栓塞和多个重叠支架置入(6例患者)。毁损性手术是指弹簧圈栓塞联合对母动脉夹层段进行近端弹簧圈封堵(CE + PT)。共有16例患者为PICA前型,其中9例为代偿型,7例为非代偿型。在代偿型中,4例行弹簧圈栓塞联合对母动脉夹层段进行近端弹簧圈封堵(CE + PT),5例行支架辅助弹簧圈栓塞(支架/弹簧圈)。在非代偿型中,6例行支架/弹簧圈,1例行多个重叠支架置入(支架)。9例患者为PICA内型,其中5例为代偿型,4例为非代偿型。在代偿型中,所有患者均行支架/弹簧圈。在非代偿型中,2例行支架/弹簧圈,2例行多个重叠支架置入(支架)。14例患者为PICA后型,其中8例为代偿型,6例为非代偿型。在代偿型中,6例行CE + PT,1例行支架/弹簧圈,1例行支架。在非代偿型中,4例行支架/弹簧圈,2例行支架。总计,10例行CE + PT,23例行支架/弹簧圈,6例行支架。围手术期并发症发生率为7.7%(3/39),与这些并发症相关的死亡率为5.1%(2/39)。在接受长期反复血管造影检查随访的36例患者中,28例(77.8%)患者实现完全闭塞。使用改良Rankin量表进行临床结局评估,结果如下:36例患者评分为0 - 2分,3例患者评分为3 - 6分。基于DAVA位置、血流动力学、形态学特征和发病方式的分类对于血管内治疗方法的选择是安全有效的。