From the Departments of *Nuclear Medicine, †Gastroenterology, and ‡Endocrinology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China.
Clin Nucl Med. 2017 Apr;42(4):310-311. doi: 10.1097/RLU.0000000000001563.
A 32-year-old man with endogenous hyperinsulinemic hypoglycemia was clinically diagnosed with an insulinoma. Conventional imaging result was negative, and a previous exploratory laparotomy with distal pancreatectomy failed to detect the tumor. Ga-exendin-4 PET/CT showed a lesion with intense radioactivity in the head of the pancreas suggestive of an insulinoma, and endoscopic ultrasound-guided ethanol ablation was performed. Postablation evaluation with Ga-exendin-4 PET/CT showed markedly decreased radioactivity of the tumor. The symptoms and blood glucose monitoring also suggested partial response of the insulinoma.
一位 32 岁男性因内源性高胰岛素血症低血糖被临床诊断为胰岛素瘤。常规影像学检查结果为阴性,之前的剖腹探查术和胰尾切除术未能发现肿瘤。Ga-胰高血糖素原-4 PET/CT 显示胰腺头部有一个病灶,放射性活性强,提示为胰岛素瘤,行内镜超声引导下乙醇消融术。Ga-胰高血糖素原-4 PET/CT 消融后评估显示肿瘤放射性活性明显降低。症状和血糖监测也提示胰岛素瘤部分缓解。