Shiraishi H
Seishin Shinkeigaku Zasshi. 1989;91(6):379-400.
In order to investigate the relationship between the impatient behavior and attention deficit of schizophrenics, eye movements during visual scanning tasks were recorded by electro-oculogram in 50 chronic schizophrenics, 20 remitted schizophrenics and 50 normal controls. Ten rows of 9 to 11 star-marks, 1 degree in size, and separated 5 degrees from each other on the inner wall of Goldman's perimeter were used as the stimulus pattern. In the practice task, subjects were instructed to scan for 1 minute star-marks one by one in a definite order indicated by the arrows on the perimeter with an interval of 2 seconds, which was regulated by the sounding of a buzzer. Then in the slow task, subjects were instructed to scan and count star-marks with the same tempo as in the practice task without the cue from the buzzer. Immediately after the slow task, each subject was asked to estimate the passage of time and the personal impression of tempo regulation in the task. Horizontal and vertical vectors of eye movements were recorded electro-oculographically through electrodes at the outer canthi of each eye and from above and below the right eye (time constant 3 sec.). The average scanning tempo, the number of inappropriate fixation and the number of spontaneous blinking were analysed in both tasks. The test-retest reliability of the slow task was sufficiently high in 20 chronic schizophrenics. In the practice task, the average scanning tempo was almost the same among 3 groups, while in the slow task, the average scanning tempo of chronic schizophrenics was significantly faster than normal controls and remitted schizophrenics. The scanning tempo of chronic schizophrenics was faster at the first row and had the tendency to increase afterwards. The chronic schizophrenics estimated the tempo at which they scanned and the passage of time overly longer than normal controls and remitted schizophrenics. Thirteen items of BPRS (Brief Psychiatric Rating Scale) were significantly correlated with the average scanning tempo and the pattern of smooth pursuit eye movements with rectangular saccades was associated with the fastness of the average scanning tempo. The number of inappropriate fixation and the spontaneous blinking were significantly correlated with average scanning tempo in chronic schizophrenics and remitted schizophrenics but not in normal controls.(ABSTRACT TRUNCATED AT 400 WORDS)
为了研究精神分裂症患者的急躁行为与注意力缺陷之间的关系，通过眼电图记录了50例慢性精神分裂症患者、20例康复期精神分裂症患者和50名正常对照者在视觉扫描任务中的眼动情况。在戈德曼视野计内壁上使用十排9至11个大小为1度、彼此间隔5度的星号作为刺激模式。在练习任务中，受试者被指示按照视野计上箭头所示的确定顺序，以2秒的间隔逐个扫描星号1分钟，这由蜂鸣器的声音调节。然后在慢速任务中，受试者被指示以与练习任务相同的节奏扫描并计数星号，且没有蜂鸣器的提示。在慢速任务结束后，立即要求每个受试者估计时间的流逝以及对任务中节奏调节的个人感受。通过位于每只眼睛外眦以及右眼上方和下方的电极，以眼电图方式记录眼动的水平和垂直向量（时间常数3秒）。分析了两项任务中的平均扫描节奏、不适当注视的次数和自发眨眼的次数。在20例慢性精神分裂症患者中，慢速任务的重测信度足够高。在练习任务中，三组之间的平均扫描节奏几乎相同，而在慢速任务中，慢性精神分裂症患者的平均扫描节奏明显快于正常对照者和康复期精神分裂症患者。慢性精神分裂症患者在第一排的扫描节奏更快，且之后有加快的趋势。慢性精神分裂症患者估计他们扫描的节奏和时间的流逝比正常对照者和康复期精神分裂症患者长得多。简明精神病评定量表（BPRS）的13项与平均扫描节奏显著相关，矩形扫视的平稳跟踪眼动模式与平均扫描节奏的快慢相关。在慢性精神分裂症患者和康复期精神分裂症患者中，不适当注视的次数和自发眨眼与平均扫描节奏显著相关，但在正常对照者中并非如此。（摘要截短至400字）
