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经尿道膀胱侧壁肿瘤切除术中闭孔神经阻滞对肿瘤标本中逼尿肌存在情况及疾病复发的影响。

Effect of obturator nerve block during transurethral resection of lateral bladder wall tumors on the presence of detrusor muscle in tumor specimens and recurrence of the disease.

作者信息

Erbay Guven, Akyol Fethi, Karabakan Mehmet, Celebi Bulent, Keskin Ercument, Hirik Erkan

机构信息

Department of Urology, Erzincan University Mengucek Gazi Research and Training Hospital, Erzincan, Turkey.

Department of Anesthesiology, Erzincan University Mengücek Gazi Training and Research Hospital, Erzincan, Turkey.

出版信息

Kaohsiung J Med Sci. 2017 Feb;33(2):86-90. doi: 10.1016/j.kjms.2016.11.006. Epub 2016 Dec 30.

Abstract

We investigated the effect of spinal anesthesia combined with obturator nerve block (ONB) during the transurethral resection of lateral bladder wall tumors (TUR-BT) on the presence of detrusor muscle tissue in tumor specimens and on tumor recurrence. TUR-BT was performed on 96 patients with a lateral bladder wall tumor under spinal anesthesia in our clinic between January 2011 and December 2015. The patients were divided into two groups: 49 patients only received spinal anesthesia and 47 patients received spinal anesthesia combined with ONB. The groups were retrospectively compared in terms of adductor muscle contraction, bladder perforation, complete tumor resection, presence of muscle tissue in the pathology material, and recurrence rate during follow-up. The obturator reflex was significantly observed in the non-ONB group (p < 0.05). In the ONB group, the percentages of complete resection and detrusor muscle tissue were significantly higher (p = 0.003 and p = 0.001, respectively). The postoperative recurrence rate was found to be significantly higher in the non-ONB group than in the ONB group (p = 0.025). Spinal anesthesia combined with ONB during TUR-BT prevent obturator reflex and facilitate complete resection including detrusor muscle tissue, independent from the size or number of tumors, thus reducing the recurrence of the disease.

摘要

我们研究了在经尿道膀胱侧壁肿瘤切除术(TUR-BT)期间,脊髓麻醉联合闭孔神经阻滞(ONB)对肿瘤标本中逼尿肌组织的存在情况以及肿瘤复发的影响。2011年1月至2015年12月期间,我们诊所对96例患有膀胱侧壁肿瘤的患者在脊髓麻醉下进行了TUR-BT。患者分为两组:49例患者仅接受脊髓麻醉,47例患者接受脊髓麻醉联合ONB。对两组患者在随访期间的内收肌收缩、膀胱穿孔、肿瘤完全切除、病理材料中肌肉组织的存在情况以及复发率进行回顾性比较。在非ONB组中明显观察到闭孔反射(p < 0.05)。在ONB组中,完全切除率和逼尿肌组织百分比显著更高(分别为p = 0.003和p = 0.001)。发现非ONB组的术后复发率显著高于ONB组(p = 0.025)。TUR-BT期间脊髓麻醉联合ONB可预防闭孔反射,并有助于包括逼尿肌组织在内的完全切除,与肿瘤的大小或数量无关,从而降低疾病复发率。

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