Gómez Gámez A, Sánchez de Badajoz E, García Caballero M, Gutstein Feldman D, Vara Thorbeck C
Rev Esp Enferm Apar Dig. 1989 Aug;76(2):121-4.
An attempt was made to modify postoperative ileus in rats by using different drugs (propranolol, phentolamine, neostigmine and mepivacaine). The election of these drugs was based on their effect on the extrinsic innervation of the digestive tract. No statistically appreciable acceleration of the intestinal transit was found in any case, but we observed on radiography that the injection of mepivacaine accelerated gastric emptying.
人们尝试使用不同药物（普萘洛尔、酚妥拉明、新斯的明和甲哌卡因）来改善大鼠术后肠梗阻。选择这些药物是基于它们对消化道外在神经支配的作用。在任何情况下均未发现肠道转运有统计学上显著的加速，但我们通过X光检查观察到，注射甲哌卡因可加速胃排空。
