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动脉瘤性蛛网膜下腔出血后发生脑桥外髓鞘溶解症(一例报告及文献综述)

Extrapontine myelinolysis developed after aneurysmal subarachnoid hemorrhage (a case report and literature review).

作者信息

Goroshchenko S A, Ivanov A Yu, Rozhchenko L V, Ivanova N E, Zabrodskaya Yu M, Razmologova O Yu, Kondrat'ev A N, Potemkina E G, Dmitrievskaya A Yu, Blagorazumova G P, Radzhabov S D, Petrov A E, Ivanov A A, Sinitsyn P S, Bobinov V V

机构信息

Polenov Russian Scientific Research Institute of Neurosurgery, the Branch of the Almazov Federal North-West Medical Research Centre, St. Petersburg, Russia.

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 2016;80(6):82-87. doi: 10.17116/neiro201680682-87.

DOI:10.17116/neiro201680682-87
PMID:28139577
Abstract

TOPICALITY

Central pontine and extrapontine myelinolysis is a rare and dangerous form of the demyelinating process of undefined origin, the development of which is associated with a very low sodium level in the blood (hypernatremia).

OBJECTIVE

To describe a rare case of extrapontine myelinolysis as a complication occurring in the hemorrhagic period of anterior communicating artery aneurysm rupture as well as to demonstrate that this condition can be diagnosed intravitally.

CONCLUSION

Clinical vigilance of extrapontine myelinolysis may promote the timely diagnosis and treatment of this disease, which is a potential cause of death. Pulse-therapy with glucocorticoids provides the opportunity to achieve regression of neurological symptoms and to stabilize the patient's condition.

摘要

研究热点

脑桥中央髓鞘溶解症和脑桥外髓鞘溶解症是一种罕见且危险的脱髓鞘疾病,病因不明,其发展与血液中极低的钠水平(高钠血症)有关。

目的

描述1例罕见的脑桥外髓鞘溶解症,该病例为前交通动脉瘤破裂出血期出现的并发症,并证明这种情况可在生前诊断。

结论

对脑桥外髓鞘溶解症保持临床警惕性,可能有助于及时诊断和治疗这种潜在的致死性疾病。糖皮质激素冲击治疗为使神经症状消退和稳定患者病情提供了机会。

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