肥胖 Zucker 大鼠的呼吸气体交换

Respiratory gaseous exchange in the Zucker rat.

作者信息

Refinetti R, Carlisle H J, Horvath S M

机构信息

Institute of Environmental Stress, University of California, Santa Barbara 93106.

出版信息

Respir Physiol. 1989 Oct;78(1):1-6. doi: 10.1016/0034-5687(89)90137-0.

DOI:10.1016/0034-5687(89)90137-0

PMID:2813983

Abstract

Measurements were made of the oxygen consumption and carbon dioxide production of lean and obese Zucker rats ranging from 4 to 400 days of age. As expected, O2 consumption per animal increased with age and was higher in obese than in lean rats. However, O2 consumption was lower in obese animals when expressed per unit of metabolic body mass. Age per se did not influence the respiratory quotient (R), but obese animals had consistently higher Rs than lean animals. These results confirm and extend previous findings described in the literature.

摘要

对4至400日龄的瘦型和肥胖型 Zucker 大鼠的耗氧量和二氧化碳生成量进行了测量。正如预期的那样，每只动物的耗氧量随年龄增加，且肥胖大鼠的耗氧量高于瘦型大鼠。然而，以每单位代谢体重表示时，肥胖动物的耗氧量较低。年龄本身并不影响呼吸商（R），但肥胖动物的呼吸商始终高于瘦型动物。这些结果证实并扩展了文献中描述的先前发现。