Santos Mary D, Milross Maree A, Eisenhuth John P, Alison Jennifer A
Clinical and Rehabilitation Sciences, University of Sydney, Lidcombe, New South Wales 2141, Australia.
Department of Physiotherapy, Prince of Wales Hospital, Barker Street, Randwick, New South Wales 2031, Australia.
Respir Care. 2017 Apr;62(4):444-450. doi: 10.4187/respcare.05164. Epub 2017 Jan 31.
Positive expiratory pressure (PEP) devices are used to assist with airway clearance. Little is known about the therapist-made or commercially available bubble-PEP devices. The aim of this study was to determine the end-expiratory pressures (cm HO) and oscillation frequencies (Hz) generated when a range of flows were applied to the therapist-made bubble-PEP devices (Bubble-PEP-3cm and Bubble-PEP-0cm) and commercial bubble-PEP devices (AguaPEP, Hydrapep, and Therabubble).
This was a bench-top experimental study using a compressed air source, flow rotameter (flows of 5, 10, 15, 20, and 25 L/min), and pressure transducer. Data were collected using a data acquisition device with PhysioDAQxs software and analyzed with Breathalyser software to determine the pressures and oscillation frequencies generated by 5 bubble-PEP devices. Each flow was constant for a 30-s measurement period, and measurements were repeated in triplicate. The 5 devices were: a therapist-made Bubble-PEP-3cm device (filled with 13 cm of water, tubing resting 3 cm from the base of the container); the therapist-made Bubble-PEP-0cm (filled with 10 cm of water, tubing resting at the base of the container); and the AguaPEP, Hydrapep, and Therabubble devices with water to the 10 cm mark on the containers.
Flows of 5-25 L/min produced the following mean ± SD PEP and oscillation frequencies (Hz): the Bubble-PEP-3cm produced PEP of 10.4 ± 0.14 to 10.8 ± 0.24 cm HO, oscillations between 13 and 17 Hz; the Bubble-PEP-0cm produced PEP of 10.9 ± 0.01 to 12.9 ± 0.08 cm HO, oscillations between 12 and 14 Hz; the AguaPEP produced PEP from 9.7 ± 0.02 to 11.5 ± 0.02 cm HO, oscillations between 11 and 17 Hz; the Hydrapep produced PEP of 9.6 ± 0.35 to 10.7 ± 0.39 cm HO, oscillations between 14 and 17 Hz; and the Therabubble produced PEP from 8.6 ± 0.01 to 12.8 ± 0.03 cm HO, oscillations between 14 and 17 Hz.
Bubble-PEP-3cm maintained the most stable pressure throughout the range of flows tested. All devices investigated produced similar oscillation frequencies.
呼气末正压（PEP）装置用于辅助气道清理。对于治疗师自制或市售的气泡式PEP装置，人们了解甚少。本研究的目的是确定当对治疗师自制的气泡式PEP装置（Bubble - PEP - 3cm和Bubble - PEP - 0cm）以及市售气泡式PEP装置（AguaPEP、Hydrapep和Therabubble）施加一系列气流时所产生的呼气末压力（厘米水柱）和振荡频率（赫兹）。
这是一项台式实验研究，使用压缩空气源、流量转子流量计（流量为5、10、15、20和25升/分钟）以及压力传感器。使用带有PhysioDAQxs软件的数据采集装置收集数据，并使用Breathalyser软件进行分析，以确定5种气泡式PEP装置所产生的压力和振荡频率。每个流量在30秒的测量期内保持恒定，测量重复三次。这5种装置分别是：一种治疗师自制的Bubble - PEP - 3cm装置（装有13厘米深的水，管道距容器底部3厘米）；治疗师自制的Bubble - PEP - 0cm（装有10厘米深的水，管道位于容器底部）；以及容器内水位达到10厘米标记的AguaPEP、Hydrapep和Therabubble装置。
5 - 25升/分钟的流量产生了以下平均±标准差的PEP和振荡频率（赫兹）：Bubble - PEP - 3cm产生的PEP为10.4±0.14至10.8±0.24厘米水柱，振荡频率在13至17赫兹之间；Bubble - PEP - 0cm产生的PEP为10.9±0.01至12.9±0.08厘米水柱，振荡频率在12至14赫兹之间；AguaPEP产生的PEP为9.7±0.02至11.5±0.02厘米水柱，振荡频率在11至17赫兹之间；Hydrapep产生的PEP为9.6±0.35至10.7±0.39厘米水柱，振荡频率在14至17赫兹之间；Therabubble产生的PEP为8.6±0.01至12.8±0.03厘米水柱，振荡频率在14至17赫兹之间。
在测试的所有流量范围内，Bubble - PEP - 3cm保持了最稳定的压力。所有研究的装置产生的振荡频率相似。
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