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斜带石斑鱼卵巢腔形成过程中脑内芳香化酶、类固醇受体、促性腺激素释放激素和促性腺激素的基因表达

Gene Expression of Aromatases, Steroid Receptor, GnRH and GTHs in the Brain during the Formation of Ovarian Cavity in Red Spotted Grouper, .

作者信息

Kim Hyun Kyu, Kim Jung-Hyun, Baek Hea Ja, Kwon Joon Yeong

机构信息

Dept. of Aquatic Life Medical Science, Sunmoon University, Asan 31460, Korea.

Dept. of Marine Biology, Pukyong National University, Busan 48513, Korea.

出版信息

Dev Reprod. 2016 Dec;20(4):367-377. doi: 10.12717/DR.2016.20.4.367. Epub 2016 Dec 31.

DOI:10.12717/DR.2016.20.4.367
PMID:28144641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5270611/
Abstract

Red spotted grouper, , is a popular aquaculture species and a protogynous hermaphrodite. Induction of artificial sex change at the time of primary sex differentiation is of interest but has not been successful due to the lack of necessary basic information. To find out the potential neuroendocrine influence on the primary sex differentiation, the expression of key genes in the brain was investigated during the formation of ovarian cavity. Expression of , , , , and in the brain was positively associated with the formation of ovarian cavity, showing gradual increase as the formation proceeds. However, the expression of was suppressed during the early part of the ovarian cavity formation, signifying potential hypothalamic influence on the primary sex differentiation in this species.

摘要

红斑石斑鱼是一种受欢迎的水产养殖品种,是一种雌性先熟的雌雄同体鱼类。在初级性别分化时诱导人工性逆转很有意义,但由于缺乏必要的基础信息尚未成功。为了探究潜在的神经内分泌对初级性别分化的影响,在卵巢腔形成过程中研究了大脑中关键基因的表达。大脑中、、、、和的表达与卵巢腔的形成呈正相关,随着形成过程逐渐增加。然而,在卵巢腔形成的早期阶段表达受到抑制,这表明该物种下丘脑对初级性别分化可能存在影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/86a9baf35d87/dr-20-4-367-g8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/0ce51da03124/dr-20-4-367-g1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/2ed5e414b008/dr-20-4-367-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/a77d35608739/dr-20-4-367-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/4e8055daf674/dr-20-4-367-g5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/3041e698da97/dr-20-4-367-g6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/3322c746b57d/dr-20-4-367-g7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/86a9baf35d87/dr-20-4-367-g8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/0ce51da03124/dr-20-4-367-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/77f18a725307/dr-20-4-367-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/2ed5e414b008/dr-20-4-367-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/a77d35608739/dr-20-4-367-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/4e8055daf674/dr-20-4-367-g5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/3041e698da97/dr-20-4-367-g6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/3322c746b57d/dr-20-4-367-g7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5288/5270611/86a9baf35d87/dr-20-4-367-g8.jpg

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本文引用的文献

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Dev Growth Differ. 1985;27(6):701-708. doi: 10.1111/j.1440-169X.1985.00701.x.
2
Early Gonadal Differentiation of the Protogynous Red Spotted Grouper, Epinephelus akaara.雌性先熟的赤点石斑鱼(Epinephelus akaara)的早期性腺分化
Dev Reprod. 2015 Dec;19(4):209-15. doi: 10.12717/DR.2015.19.4.209.
3
Sexual dimorphism in the brain aromatase expression and activity, and in the central expression of other steroidogenic enzymes during the period of sex differentiation in monosex rainbow trout populations.
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Front Endocrinol (Lausanne). 2019 May 15;10:304. doi: 10.3389/fendo.2019.00304. eCollection 2019.
4
Molecular cloning, characterization, and mRNA expression of gonadotropins during larval development in turbot (Scophthalmus maximus).分子克隆、特性分析及鲆鱼(大菱鲆)幼鱼发育过程中促性腺激素的 mRNA 表达。
Fish Physiol Biochem. 2019 Oct;45(5):1697-1707. doi: 10.1007/s10695-019-00656-z. Epub 2019 May 16.
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Gen Comp Endocrinol. 2008 Aug;158(1):131-7. doi: 10.1016/j.ygcen.2008.05.016. Epub 2008 Jul 2.
9
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10
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Gen Comp Endocrinol. 2007 Jan 1;150(1):75-86. doi: 10.1016/j.ygcen.2006.07.012. Epub 2006 Sep 8.