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儿童和成人青光眼引流装置手术:结局与并发症的比较研究

Glaucoma drainage device surgery in children and adults: a comparative study of outcomes and complications.

作者信息

Mandalos Achilleas, Sung Velota

机构信息

Birmingham and Midland Eye Centre, Sandwell and West Birmingham Hospitals NHS Trust, Dudley Road, Birmingham, B18 7QH, UK.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2017 May;255(5):1003-1011. doi: 10.1007/s00417-017-3584-2. Epub 2017 Feb 1.

Abstract

PURPOSE

To compare the postoperative outcomes and complications of glaucoma drainage device (GDD) surgery in pediatric (<18 years old) and adult patients.

METHODS

Retrospective, comparative study including all patients who underwent Baervedlt or Molteno device surgery by the same surgeon. Success criteria included postoperative intraocular pressure (IOP) between 6 and 21 mmHg and a 20% reduction from baseline.

RESULTS

Fifty-two children (69 eyes) and 130 adults (145 eyes) were included. Mean IOP and number of medications were significantly reduced postoperatively in both groups. Overall failure rate was similar in children and adults. However, GDD failed earlier in adults than in children. Hypotony was the most common complication in both groups in the first 6 months postoperatively. Later on, bleb encapsulation was more frequent in children, while corneal decompensation tended to be more frequent and occurred earlier in adults. Children also had a higher rate of infectious endophthalmitis and required tube repositioning more frequently than adults.

CONCLUSIONS

GDD surgery presents different postoperative challenges in children and adults, and the surgeon should remain vigilant for complications throughout the postoperative period, especially for signs of endophthalmitis or bleb encapsulation in pediatric patients. On the other hand, adults may be more prone to early corneal decompensation.

摘要

目的

比较小儿(<18岁)和成年患者青光眼引流装置(GDD)手术的术后结果及并发症。

方法

回顾性比较研究,纳入由同一位外科医生实施Baervedlt或Molteno装置手术的所有患者。成功标准包括术后眼压(IOP)在6至21 mmHg之间且较基线降低20%。

结果

纳入52名儿童(69只眼)和130名成人(145只眼)。两组术后平均眼压和用药数量均显著降低。儿童和成人的总体失败率相似。然而,GDD在成人中比在儿童中更早失败。低眼压是两组术后前6个月最常见的并发症。之后,儿童中滤过泡包裹更常见,而成人角膜失代偿往往更常见且发生更早。儿童感染性眼内炎的发生率也更高,且比成人更频繁地需要重新调整引流管位置。

结论

GDD手术在儿童和成人中呈现不同的术后挑战,外科医生在术后整个期间应警惕并发症,尤其是小儿患者的眼内炎或滤过泡包裹迹象。另一方面,成人可能更容易早期发生角膜失代偿。

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