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用于结直肠癌肝转移腹腔镜肝半肝切除术前规划的经济实惠、个性化、3D 打印肝脏模型。

Cost-effective, personalized, 3D-printed liver model for preoperative planning before laparoscopic liver hemihepatectomy for colorectal cancer metastases.

机构信息

2nd Department of General Surgery, Jagiellonian University Medical College, Kopernika 21 St., 31-501, Kraków, Poland.

出版信息

Int J Comput Assist Radiol Surg. 2017 Dec;12(12):2047-2054. doi: 10.1007/s11548-017-1527-3. Epub 2017 Jan 31.


DOI:10.1007/s11548-017-1527-3
PMID:28144830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5702382/
Abstract

PURPOSE: Three-dimensional (3D) printing for preoperative planning has been intensively developed in the recent years. However, the implementation of these solutions in hospitals is still difficult due to high costs, extremely expensive industrial-grade printers, and software that is difficult to obtain and learn along with a lack of a defined process. This paper presents a cost-effective technique of preparing 3D-printed liver models that preserves the shape and all of the structures, including the vessels and the tumor, which in the present case is colorectal liver metastasis. METHODS: The patient's computed tomography scans were used for the separation and visualization of virtual 3D anatomical structures. Those elements were transformed into stereolithographic files and subsequently printed on a desktop 3D printer. The multipart structure was assembled and filled with silicone. The patient underwent subsequent laparoscopic right hemihepatectomy. The entire process is described step-by-step, and only free-to-use and mostly open-source software was used. RESULTS: As a result, a transparent, full-sized liver model with visible vessels and colorectal metastasis was created for under $150, which-taking into account 3D printer prices-is much cheaper than models presented in previous research papers. CONCLUSIONS: The increased accessibility of 3D models for physicians before complex laparoscopic surgical procedures such as hepatic resections could lead to beneficial breakthroughs in these sophisticated surgeries, as many reports show that these models reduce operative time and improve short term outcomes.

摘要

目的:近年来,三维(3D)打印在术前规划中得到了广泛的发展。然而,由于成本高、极其昂贵的工业级打印机、难以获得和学习的软件以及缺乏明确的流程,这些解决方案在医院的实施仍然很困难。本文提出了一种经济有效的 3D 打印肝脏模型的制备技术,该技术可以保留形状和所有结构,包括血管和肿瘤,在本案例中是结直肠癌肝转移。

方法:使用患者的计算机断层扫描来分离和可视化虚拟 3D 解剖结构。这些元素被转化为立体光刻文件,然后在桌面 3D 打印机上打印。将多部分结构组装并填充硅酮。患者随后接受了腹腔镜右半肝切除术。整个过程按步骤进行描述,仅使用免费和大多是开源的软件。

结果:结果,创建了一个透明的、全尺寸的肝脏模型,可看到血管和结直肠转移,成本低于 150 美元,考虑到 3D 打印机的价格,比之前研究论文中介绍的模型便宜得多。

结论:在复杂的腹腔镜手术(如肝切除术)前增加医生对 3D 模型的获取途径,可能会在这些复杂手术中带来有益的突破,因为许多报告表明这些模型可以缩短手术时间并改善短期结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfe1/5702382/15ee2ebb693c/11548_2017_1527_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfe1/5702382/2d26abd57b72/11548_2017_1527_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfe1/5702382/2d6c89b63b52/11548_2017_1527_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfe1/5702382/76b8f7ca2486/11548_2017_1527_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfe1/5702382/6af7b761e419/11548_2017_1527_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfe1/5702382/15ee2ebb693c/11548_2017_1527_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfe1/5702382/2d26abd57b72/11548_2017_1527_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfe1/5702382/2d6c89b63b52/11548_2017_1527_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfe1/5702382/76b8f7ca2486/11548_2017_1527_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfe1/5702382/6af7b761e419/11548_2017_1527_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfe1/5702382/15ee2ebb693c/11548_2017_1527_Fig5_HTML.jpg

相似文献

[1]
Cost-effective, personalized, 3D-printed liver model for preoperative planning before laparoscopic liver hemihepatectomy for colorectal cancer metastases.

Int J Comput Assist Radiol Surg. 2017-1-31

[2]
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[3]
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[6]
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[8]
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[10]
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引用本文的文献

[1]
The evolution of anatomical hepatectomy: Past, present, and future.

ILIVER. 2022-10-11

[2]
Randomized comparison of AI enhanced 3D printing and traditional simulations in hepatobiliary surgery.

NPJ Digit Med. 2025-6-2

[3]
Liver Phantoms Cast in 3D-Printed Mold for Image-Guided Procedures.

Diagnostics (Basel). 2024-7-15

[4]
Quality assurance of 3D-printed patient specific anatomical models: a systematic review.

3D Print Med. 2024-3-27

[5]
Utilization of 3D printing technology in hepatopancreatobiliary surgery.

J Zhejiang Univ Sci B. 2024-2-15

[6]
Three-Dimensional Printing and Bioprinting in Renal Transplantation and Regenerative Medicine: Current Perspectives.

J Clin Med. 2023-10-14

[7]
The Quantitative Impact of Using 3D Printed Anatomical Models for Surgical Planning Optimization: Literature Review.

3D Print Addit Manuf. 2023-10-1

[8]
Cells-in-Touch: 3D Printing in Reconstruction and Modelling of Microscopic Biological Geometries for Education and Future Research Applications.

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[9]
Microfluidic Liver-on-a-Chip for Preclinical Drug Discovery.

Pharmaceutics. 2023-4-21

[10]
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本文引用的文献

[1]
Do 3D Printing Models Improve Anatomical Teaching About Hepatic Segments to Medical Students? A Randomized Controlled Study.

World J Surg. 2016-8

[2]
3D Printout Models vs. 3D-Rendered Images: Which Is Better for Preoperative Planning?

J Surg Educ. 2016

[3]
Advantages and disadvantages of 3-dimensional printing in surgery: A systematic review.

Surgery. 2016-6

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Personalized 3D printed model of kidney and tumor anatomy: a useful tool for patient education.

World J Urol. 2016-3

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Emerging Applications of Bedside 3D Printing in Plastic Surgery.

Front Surg. 2015-6-16

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Pediatr Surg Int. 2015-6

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Plant Cell. 2015-4

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Developing a parametric ear model for auricular reconstruction: a new step towards patient-specific implants.

J Craniomaxillofac Surg. 2015-4

[9]
Medical Applications for 3D Printing: Current and Projected Uses.

P T. 2014-10

[10]
Application of a three-dimensional print of a liver in hepatectomy for small tumors invisible by intraoperative ultrasonography: preliminary experience.

World J Surg. 2014-12

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