Helm C A, Israelachvili J N, McGuiggan P M
Department of Chemical and Nuclear Engineering, University of California, Santa Barbara 93106.
Science. 1989 Nov 17;246(4932):919-22. doi: 10.1126/science.2814514.
The surface forces apparatus technique was used for measuring the adhesion, deformation, and fusion of bilayers supported on mica surfaces in aqueous solutions. The most important force leading to the direct fusion of bilayers is the hydrophobic interaction, although the occurrence of fusion is not simply related to the force law between bilayers. Bilayers do not need to "overcome" some repulsive force barrier, such as hydration, before they can fuse. Instead, once bilayer surfaces come within about 1 nanometer of each other, local deformations and molecular rearrangements allow them to "bypass" these forces.
表面力仪技术用于测量水溶液中云母表面支撑的双层膜的粘附、变形和融合。导致双层膜直接融合的最重要力量是疏水相互作用，尽管融合的发生并不简单地与双层膜之间的力定律相关。双层膜在融合之前不需要“克服”一些排斥力屏障，如水合作用。相反，一旦双层膜表面彼此靠近到约1纳米以内，局部变形和分子重排就使它们能够“绕过”这些力。
