State Key Laboratory of Crystal Materials, Shandong University , Jinan 250100, China.
Department of Obstetrics and Gynecology, Peking University Third Hospital , Beijing 100191, China.
ACS Nano. 2017 Feb 28;11(2):1973-1981. doi: 10.1021/acsnano.6b08140. Epub 2017 Feb 8.
Terbium-aspartic acid (Tb-Asp) nanocrystals with chirality-dependent tunable fluorescent properties can be synthesized through a facile synthesis method through the coordination between Tb and Asp. Asp with different chirality (dextrorotation/d and levogyration/l) changes the stability of the coordination center following fluorescent absorption/emission ability differences. Compared with l-Asp, d-Asp can coordinate Tb to form a more stable center, following the higher quantum yield and longer fluorescence life. Fluorescence intensity of Tb-Asp linearly increases with increase ratio of d-Asp in the mixed chirality Tb-Asp system, and the fluorescent properties of Tb-Asp nanocrystals can be tuned by adjusting the chirality ratio. Tb-Asp nanocrystals possess many advantage, such as high biocompatibility, without any color in visible light irradiation, monodispersion with very small size, and long fluorescent life. Those characteristics will give them great potential in many application fields, such as low-cost antifake markers and advertisements using inkjet printers or for molds when dispersed in polydimethylsiloxane. In addition, europium can also be used to synthesize Eu-Asp nanoparticles. Importantly, the facile, low-cost, high-yield, mass-productive "green" process provides enormous advantages for synthesis and application of fluorescent nanocrystals, which will have great impact in nanomaterial technology.
通过 Tb 和 Asp 之间的配位，可通过简便的合成方法合成具有手性依赖性可调荧光性质的铽-天冬氨酸（Tb-Asp）纳米晶体。不同手性（右旋/d 和左旋/l）的 Asp 改变了配位中心的稳定性，从而导致荧光吸收/发射能力的差异。与 l-Asp 相比，d-Asp 可以与 Tb 配位形成更稳定的中心，具有更高的量子产率和更长的荧光寿命。在混合手性 Tb-Asp 体系中，随着 d-Asp 比例的增加，Tb-Asp 的荧光强度呈线性增加，并且可以通过调节手性比例来调节 Tb-Asp 纳米晶体的荧光性质。Tb-Asp 纳米晶体具有许多优点，例如高生物相容性、在可见光照射下没有任何颜色、单分散且非常小的尺寸、以及长荧光寿命。这些特性使其在许多应用领域具有巨大的潜力，例如用于低成本防伪标记和喷墨打印机使用的广告，或者在分散于聚二甲基硅氧烷中时作为模具。此外，还可以使用铕来合成 Eu-Asp 纳米颗粒。重要的是，这种简便、低成本、高产率、大规模生产的“绿色”工艺为荧光纳米晶体的合成和应用提供了巨大的优势，这将对纳米材料技术产生重大影响。
