Soria Claudia, Nieto Nelson, Villacís José E, Lainez Sara, Cartelle Mónica
Laboratorio de Bacteriología, Hospital del niño Dr. Francisco de Icaza Bustamante, Guayaquil, Ecuador,
Comité de Control de infecciones asociadas a los cuidados de la salud, Hospital del niño Dr. Francisco de Icaza Bustamante, Guayaquil, Ecuador.
Rev Chilena Infectol. 2016 Dec;33(6):703-705. doi: 10.4067/S0716-10182016000600016.
We report a Serratia marcescens outbreak occurred in the NICU of a pediatric hospital in Guayaquil, Ecuador. Nine cases of infection were detected, from which septicemia was developed in 55.5%. The index case was a newborn derived from another institution with septic arthritis caused by the outbreak strain. The infection rate was 17.6% and mortality rate was 33.3%. All isolates were resistant to aminoglycosides and susceptible to third generation cephalosporins and carbapenems. Clonality analysis by pulsed-field gel electrophoresis (PFGE) revealed the presence of two closely related clones confirming the horizontal spread. Measures were taken by the committee such as: strengthening the hand hygiene, patient hygiene and cohort studies of gastrointestinal colonization, which allowed the control of the outbreak.
我们报告了一起在厄瓜多尔瓜亚基尔一家儿科医院新生儿重症监护病房发生的粘质沙雷氏菌暴发事件。检测到9例感染病例，其中55.5%发展为败血症。首例病例是一名来自另一家机构的新生儿，患有由暴发菌株引起的化脓性关节炎。感染率为17.6%，死亡率为33.3%。所有分离株均对氨基糖苷类耐药，对第三代头孢菌素和碳青霉烯类敏感。通过脉冲场凝胶电泳（PFGE）进行的克隆性分析显示存在两个密切相关的克隆，证实了水平传播。委员会采取了一些措施，如：加强手卫生、患者卫生以及胃肠道定植的队列研究，从而控制了此次暴发。
