[Ultrasonic medicinal aerosols in multimodal treatment of acute surgical diseases of the organs of the abdominal cavity].

Microbiologic studies have shown that ultrasonic aerosol treatment of E. coli reference culture with 0.02% furacillin solution for 3 min reduces its survival rate by 2 orders (240-fold). Exposure to low-energy ultrasound increases 7-fold the antibacterial activity of furacillin solution. Experiments have demonstrated that 99mTc ionized particles diffusion via cadaver peritoneum is enhanced more than 5 times if Tc solution is spread via ultrasonic aerosol. A method for ultrasonic aerosol treatment of infected abdominal cavity has been developed. Clinical trials of the method have been carried out: it has been employed in multiple-modality treatment of acute surgical diseases of the abdominal organs in 6 patients and of postoperative peritonitis in 15 patients, as well as for the prevention of purulent complications after extensive abdominal surgery in 4 patients.