Paul Gunchan, Paul Birinder S, Singh Gagandeep
Department of Critical Care Medicine, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Department of Neurology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Indian J Crit Care Med. 2016 Dec;20(12):731-734. doi: 10.4103/0972-5229.195713.
Varicella infection is common in children caused by varicella-zoster virus (VZV). VZV is known to cause cerebral arterial vasculopathy and antibody-mediated hypercoagulable state leading to thrombotic complications in children. Such complications in adults are very rare. We report three cases that represent the unseen face of primary varicella infection in adults. Simultaneous involvement of cortical venous sinus thrombosis and deep vein thrombosis leading to clot in right atrium and pulmonary embolism in first case; cortical venous sinus thrombosis in second case; and deep vein thrombosis in third case. Early diagnosis and management can help prevent associated morbidity and mortality.
水痘感染在儿童中很常见,由水痘-带状疱疹病毒(VZV)引起。已知VZV会导致儿童脑动脉血管病变和抗体介导的高凝状态,从而引发血栓并发症。这种并发症在成人中非常罕见。我们报告了三例病例,展现了成人原发性水痘感染不为人知的一面。第一例同时累及皮质静脉窦血栓形成和深静脉血栓形成,导致右心房血栓和肺栓塞;第二例为皮质静脉窦血栓形成;第三例为深静脉血栓形成。早期诊断和治疗有助于预防相关的发病率和死亡率。