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急性脑静脉窦血栓形成:原发性水痘带状疱疹病毒感染的一种罕见并发症。

Acute Cerebral Venous Sinus Thrombosis: A Rare Complication of Primary Varicella Zoster Virus Infection.

作者信息

Panwar Champa, Singh Surinder, Sharma Neeraj

机构信息

Department of Paediatrics, Indira Gandhi Medical College (IGMC), Shimla, Himachal Pradesh, India.

出版信息

J Pediatr Neurosci. 2020 Apr-Jun;15(2):116-119. doi: 10.4103/jpn.JPN_167_18. Epub 2020 Jun 27.

Abstract

Varicella-Zoster is a benign self limiting exanthematous illness in pediatric population which can rarely present with severe neurological manifestations such as cerebral venous thrombosis(CVT).We report the case of a 17-years old adolescent male with left hemiparesis, cranial nerve palsies associated with primary Varicella infection. MRI revealed cerebral venous thrombosis involving right transverse sinus, sigmoid sinus, internal jugular vein and infarct involving right cerebral hemisphere, Midbrain and Pons. The patient responded well to Acyclovir, cerebral decongestants and oral anticoagulant therapy.CVT is a rare but the most life threatening complication following primary Varicella infection and early diagnosis is essential for proper management of the patient.

摘要

水痘带状疱疹是儿科人群中一种良性自限性发疹性疾病,很少会出现严重的神经学表现,如脑静脉血栓形成(CVT)。我们报告了一例17岁青少年男性病例,其因原发性水痘感染出现左侧偏瘫、颅神经麻痹。磁共振成像(MRI)显示脑静脉血栓形成累及右侧横窦、乙状窦、颈内静脉,梗死累及右侧大脑半球、中脑和脑桥。该患者对阿昔洛韦、脑消肿药和口服抗凝治疗反应良好。CVT是原发性水痘感染后一种罕见但最具生命威胁的并发症,早期诊断对于患者的恰当治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3299/7519734/383fa863caa3/JPN-15-116-g001.jpg

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