Genes2GO：一个用于查询特定基因本体术语的基因集的网络应用程序。
Genes2GO: A web application for querying gene sets for specific GO terms.
作者信息
Chawla Konika, Kuiper Martin
机构信息
Department of Biology, Norwegian University of Science and Technology (NTNU), Hogskoleringen 5, 7491 Trondheim, Norway.
出版信息
Bioinformation. 2016 Jun 15;12(3):231-232. doi: 10.6026/97320630012231. eCollection 2016.
UNLABELLED
Gene ontology annotations have become an essential resource for biological interpretations of experimental findings. The process of gathering basic annotation information in tables that link gene sets with specific gene ontology terms can be cumbersome, in particular if it requires above average computer skills or bioinformatics expertise. We have therefore developed Genes2GO, an intuitive R-based web application. Genes2GO uses the biomaRt package of Bioconductor in order to retrieve custom sets of gene ontology annotations for any list of genes from organisms covered by the Ensembl database. Genes2GO produces a binary matrix file, indicating for each gene the presence or absence of specific annotations for a gene. It should be noted that other GO tools do not offer this user-friendly access to annotations.
AVAILABILITY
Genes2GO is freely available and listed under http://www.semantic-systems-biology.org/tools/externaltools/.
未标注
基因本体注释已成为实验结果生物学解释的重要资源。在将基因集与特定基因本体术语相联系的表格中收集基本注释信息的过程可能很繁琐，特别是如果这需要高于平均水平的计算机技能或生物信息学专业知识。因此，我们开发了Genes2GO，这是一个基于R的直观网络应用程序。Genes2GO使用Bioconductor的biomaRt包，以便从Ensembl数据库涵盖的生物体的任何基因列表中检索定制的基因本体注释集。Genes2GO生成一个二元矩阵文件，表明每个基因是否存在特定注释。应当指出，其他基因本体工具并未提供这种对注释的用户友好型访问。
可用性
Genes2GO可免费获取，列于http://www.semantic-systems-biology.org/tools/externaltools/ 。
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