Dos Santos Renan Martins, Dias-Souza Marcus Vinícius
Faculty of Pharmacy, Federal University of Minas Gerais, Brazil; Integrated Pharmacology and Drug Interactions Research Group (GPqFAR), Brazil.
Biological Sciences Institute, Federal University of Minas Gerais, Brazil; Integrated Pharmacology and Drug Interactions Research Group (GPqFAR), Brazil.
Saudi J Biol Sci. 2017 Feb;24(2):331-337. doi: 10.1016/j.sjbs.2015.09.033. Epub 2015 Oct 9.
This study aimed to investigate the antifungal effectiveness of five different formulations against dandruff and ringworm dermatophytes. was also included in our assays. Fungal susceptibility tests were performed with planktonic cells and biofilms of reference strains. Microbiological and physicochemical quality parameters were assessed for all formulations. Our data indicated that the formulations were effective against the dermatophytes strains, and to our knowledge, the effectiveness of cosmetic formulations against fungal biofilms is shown for the first time. The formulations were considered effective against the explored dermatophytes and were considered safe given the adequate microbiological and physicochemical characteristics shown in the proposed assays.
本研究旨在调查五种不同配方对头皮屑和癣类皮肤真菌的抗真菌效果。我们的检测中也包括了[此处原文缺失相关内容]。对参考菌株的浮游细胞和生物膜进行了真菌药敏试验。评估了所有配方的微生物学和物理化学质量参数。我们的数据表明，这些配方对皮肤真菌菌株有效，据我们所知，首次证明了化妆品配方对真菌生物膜的有效性。鉴于在拟议检测中显示出的足够的微生物学和物理化学特性，这些配方被认为对所研究的皮肤真菌有效且安全。
