Karpus Jason, Bosscher Michael, Ajiboye Ifedayo, Zhang Liang, He Chuan
Department of Chemistry, University of Chicago, 929 East 57th Street, Chicago, IL, 60637, USA.
Chembiochem. 2017 Apr 4;18(7):633-637. doi: 10.1002/cbic.201700051. Epub 2017 Mar 6.
Effective and cheap methods and techniques for the safe removal of hexavalent chromate from the environment are in increasingly high demand. High concentrations of hexavalent chromate have been shown to have numerous harmful effects on human biology. We show that the E. coli molybdate-binding protein ModA is a genetically encoded tool capable of removing chromate from aqueous solutions. Although previously reported to not bind chromate, we show that ModA binds chromate tightly and is capable of removing chromate to levels well below current US federal standards.
人们对从环境中安全去除六价铬的有效且廉价的方法和技术的需求日益高涨。高浓度的六价铬已被证明对人体生物学有诸多有害影响。我们发现大肠杆菌钼酸盐结合蛋白ModA是一种能够从水溶液中去除铬酸盐的基因编码工具。尽管此前报道称其不结合铬酸盐，但我们发现ModA能紧密结合铬酸盐，并能将铬酸盐去除至远低于美国现行联邦标准的水平。
