Nery E B, Lynch K L, Rooney G E
J Prosthet Dent. 1978 Dec;40(6):668-75. doi: 10.1016/0022-3913(78)90067-7.
Tricalcium phosphate ceramic, with 50% porosity and 400 to 500 micrometer pore diameter, was used to augment the edentulous alveolar ridge of 10 adult mongrel dogs. The implants were evaluated histologically at different time intervals (7, 30, 90, 180, and 360 days). Preoperative and postoperative blood chemistry studies were also evaluated. The results showed that, other than for the expected acute nonspecific inflammatory response due to the surgery, the material was well tolerated by the tissues and was nontoxic. Bone and soft tissues grew into the pores, thereby creating an excellent biomechanical bond between the ceramic implant and surrounding structures. Preoperative and postoperative blood chemistry studies demonstrated no significant change.
磷酸三钙陶瓷，孔隙率为50%，孔径为400至500微米，用于增大10只成年杂种犬的无牙牙槽嵴。在不同时间间隔（7天、30天、90天、180天和360天）对植入物进行组织学评估。还评估了术前和术后的血液化学研究。结果表明，除了手术引起的预期急性非特异性炎症反应外，该材料组织耐受性良好且无毒。骨组织和软组织长入孔隙，从而在陶瓷植入物与周围结构之间形成了良好的生物力学结合。术前和术后的血液化学研究表明无显著变化。
