Wang S A, Chen A Y, Yu Z E, Huang Z J, Wao Y M
Department of Prosthetic Dentistry, College of Stomatology, West China University of Medical Sciences, Sichuan.
J Oral Rehabil. 1989 May;16(3):229-39. doi: 10.1111/j.1365-2842.1989.tb01337.x.
A particulate BGC (bioactive glass ceramics), has been developed as a new bone graft biomaterial for alveolar ridge augmentation and has been evaluated by simulated animal models. Five beagle dogs were used in this investigation. Prior to augmentation the mandibular posterior teeth of the animals were extracted. Three months after the extractions, the porous BGC particles were packed into the subperiosteal tunnels in the ridges with a special syringe. The animals were killed at different time intervals and the specimens were examined by light microscopy, scanning electron microscopy (SEM), and X-ray energy dispersive analysis (EDAX), respectively. The results of this study indicate that the BGC particles are firmly combined with the adjacent hard and soft tissues by the bone bonding interface between the implants and the alveolar bone, and by the ingrowth of bone or fibrous connective tissue into the interspaces and the pores of the particles. The results have demonstrated that particulate BGC with pores is an excellent implant material for alveolar ridge augmentation because of its very good biocompatibility.
一种颗粒状生物活性玻璃陶瓷(BGC)已被开发为用于牙槽嵴增高的新型骨移植生物材料,并已通过模拟动物模型进行评估。本研究使用了5只比格犬。在进行增高手术前,拔除了动物的下颌后牙。拔牙3个月后,用特制注射器将多孔BGC颗粒填充到牙槽嵴的骨膜下隧道中。在不同时间间隔处死动物,分别用光学显微镜、扫描电子显微镜(SEM)和X射线能量色散分析(EDAX)对标本进行检查。本研究结果表明,BGC颗粒通过植入物与牙槽骨之间的骨结合界面,以及骨或纤维结缔组织长入颗粒的间隙和孔隙中,与相邻的硬组织和软组织牢固结合。结果表明,具有孔隙的颗粒状BGC因其良好的生物相容性,是用于牙槽嵴增高的优良植入材料。