评估软骨中环枢关节早期退变的可行性研究：轴向 Tρ、T1、T2* 成像
Feasibility study for evaluating early lumbar facet joint degeneration using axial T ρ, T , and T2* mapping in cartilage.
机构信息
Department of Spine Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, PR China.
Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, PR China.
出版信息
J Magn Reson Imaging. 2017 Aug;46(2):468-475. doi: 10.1002/jmri.25596. Epub 2017 Feb 2.
PURPOSE
To assess the feasibility of axial T , T2*, and T ρ mapping of lumbar facet joint (LFJ) cartilage for evaluation of early degeneration.
MATERIALS AND METHODS
We examined a total of 176 LFJs from 21 volunteers using axial T , T2*, and T ρ mapping with a 3.0T magnetic resonance imaging (MRI) scanner. All LFJs were measured and grouped according to the presence of low back pain (LBP), the Weishaupt grading system, and the Pfirrmann grade of the adjacent intervertebral disk (IVD). T , T2*, and T ρ values were analyzed and compared among the different groups.
RESULTS
Low interobserver agreement was found in the Weishaupt grading of LFJs (κ = 0.161). The T ρ values of LFJs were significantly different between adjacent two Pfirrmann grade of disks (grade I 50.15 ± 3.63 msec / grade II 53.27 ± 3.80 msec, P = 0.002; grade II 53.27 ± 3.80 msec / grade III 58.40 ± 4.17 msec, P < 0.01), and in different Weishaupt grades of LFJs (P = 0.000). T2* values were only found significantly different between Pfirrmann grade I and III of disks (P = 0.048). There was no significant difference in T values of LFJs whatever in Pfirrmann (P = 0.556) or Weishaupt grades (P = 0.694). No significant difference was found in T , T2*, and T ρ values between volunteers with LBP and without LBP (P = 0.783, PT2*=0.311, P ρ = 0.259).
CONCLUSION
Axial T ρ could be an effective and sensitive method to assess for early degenerative changes in LFJ cartilage.
LEVEL OF EVIDENCE
1 Technical Efficacy: Stage 2 J. MAGN. RESON. IMAGING 2017;46:468-475.
目的
评估轴向 T 、 T2* 和 T ρ 映射在腰椎小关节 (LFJ) 软骨早期退变评估中的可行性。
材料与方法
我们使用 3.0T 磁共振成像 (MRI) 扫描仪对 21 名志愿者的共 176 个 LFJ 进行了轴向 T 、 T2* 和 T ρ 成像。所有 LFJ 均根据腰痛 (LBP)、Weishaupt 分级系统和相邻椎间盘 (IVD) 的 Pfirrmann 分级进行了测量和分组。分析并比较了不同组之间的 T 、 T2* 和 T ρ 值。
结果
LFJ 的 Weishaupt 分级存在低观察者间一致性 (κ=0.161)。相邻 Pfirrmann 分级椎间盘之间的 LFJ T ρ 值存在显著差异(等级 I 50.15±3.63 msec/等级 II 53.27±3.80 msec，P=0.002；等级 II 53.27±3.80 msec/等级 III 58.40±4.17 msec，P<0.01)，并且在不同的 Weishaupt 分级的 LFJ 之间也存在显著差异(P=0.000)。仅在 Pfirrmann 分级 I 和 III 之间发现 T2* 值存在显著差异(P=0.048)。无论在 Pfirrmann 分级(P=0.556)还是在 Weishaupt 分级(P=0.694)中，LFJ 的 T 值均无显著差异。志愿者中腰痛与无腰痛之间的 T 、 T2* 和 T ρ 值无显著差异(P=0.783，PT2*=0.311，P ρ=0.259)。
结论
轴向 T ρ 可能是评估 LFJ 软骨早期退行性改变的有效且敏感的方法。
证据水平
1 技术功效：第 2 阶段 J. MAGN. RESON. IMAGING 2017；46：468-475。
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