Ackerman Ilana N, Bohensky Megan A, de Steiger Richard, Brand Caroline A, Eskelinen Antti, Fenstad Anne Marie, Furnes Ove, Graves Stephen E, Haapakoski Jaason, Mäkelä Keijo, Mehnert Frank, Nemes Szilard, Overgaard Søren, Pedersen Alma B, Garellick Göran
Monash University and University of Melbourne, Melbourne, Victoria, Australia.
University of Melbourne, Melbourne, Victoria, Australia.
Arthritis Care Res (Hoboken). 2017 Nov;69(11):1659-1667. doi: 10.1002/acr.23197. Epub 2017 Sep 26.
To compare the lifetime risk of total hip replacement (THR) surgery for osteoarthritis (OA) between countries, and over time.
Data on primary THR procedures performed for OA in 2003 and 2013 were extracted from national arthroplasty registries in Australia, Denmark, Finland, Norway, and Sweden. Life tables and population data were also obtained for each country. Lifetime risk of THR was calculated for 2003 and 2013 using registry, life table, and population data.
In 2003, lifetime risk of THR ranged from 8.7% (Denmark) to 15.9% (Norway) for females, and from 6.3% (Denmark) to 8.6% (Finland) for males. With the exception of females in Norway (where lifetime risk started and remained high), lifetime risk of THR increased significantly for both sexes in all countries from 2003 to 2013. In 2013, lifetime risk of THR was as high as 1 in 7 women in Norway, and 1 in 10 men in Finland. Females consistently demonstrated the highest lifetime risk of THR at both time points. Notably, lifetime risk for females in Norway was approximately double the risk for males in 2003 (females 15.9% [95% confidence interval (95% CI) 15.6-16.1], males 6.9% [95% CI 6.7-7.1]), and 2013 (females 16.0% [95% CI 15.8-16.3], males 8.3% [95% CI 8.1-8.5]).
Using representative, population-based data, this study found statistically significant increases in the lifetime risk of THR in 5 countries over a 10-year period, and substantial between-sex differences. These multinational risk estimates can inform resource planning for OA service delivery.
比较不同国家以及不同时期骨关节炎（OA）患者全髋关节置换术（THR）的终生风险。
从澳大利亚、丹麦、芬兰、挪威和瑞典的国家关节成形术登记处提取2003年和2013年因OA进行初次THR手术的数据。还获取了每个国家的生命表和人口数据。使用登记处、生命表和人口数据计算2003年和2013年THR的终生风险。
2003年，女性THR的终生风险在丹麦为8.7%，在挪威为15.9%；男性THR的终生风险在丹麦为6.3%，在芬兰为8.6%。除挪威女性（其终生风险开始时就很高且一直保持）外，2003年至2013年所有国家男女的THR终生风险均显著增加。2013年，挪威七分之一的女性以及芬兰十分之一的男性THR终生风险高达1。在两个时间点，女性的THR终生风险始终最高。值得注意的是，2003年挪威女性的终生风险约为男性的两倍（女性15.9% [95%置信区间（95%CI）15.6 - 16.1]，男性6.9% [95%CI 6.7 - 7.1]），2013年也是如此（女性16.0% [95%CI 15.8 - 16.3]，男性8.3% [95%CI 8.1 - 8.5]）。
本研究使用具有代表性的基于人群的数据，发现5个国家在10年期间THR的终生风险有统计学显著增加，且存在显著的性别差异。这些跨国风险估计可为OA服务提供的资源规划提供参考。
