Guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications, Institute of Photonics Technology, Jinan University, Guangzhou 510632, China.
Guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications, Institute of Photonics Technology, Jinan University, Guangzhou 510632, China.
Talanta. 2017 Apr 1;165:245-250. doi: 10.1016/j.talanta.2016.12.053. Epub 2016 Dec 25.
A sensitive Ag sensor based on nucleic acid probes modified silica microfiber interferometry is designed and developed. The probes on microfiber surface plays the part on catching Ag as tentacles, while their conformation change from random coils to hairpins. It induces the fiber surface refractive index change, which is captured by the optical fiber and translated into a significant wavelength shift in the interferometric fringe. Such a combination enables an improved concentration sensitivity of 0.22nm/log M and limit of detection of 1.36 × 10M, taking the advantage of real-time and in-situ analysis. It shows good selectivity in the present of many other metal ions and offers potential to analysis in real matrix, especially in the environmental samples must be analyzed in a short time. This may provide insights into the preparation of sensing platforms for optical quantification of other small molecular, supplementing the existing tools.
设计并开发了一种基于核酸探针修饰的硅基微光纤干涉仪的灵敏 Ag 传感器。微光纤表面上的探针起到捕捉 Ag 的作用，就像触手一样，而它们的构象从无规线团变成发夹。这导致光纤表面折射率发生变化，被光纤捕获并转化为干涉条纹中明显的波长移动。这种组合实现了 0.22nm/log M 的改进浓度灵敏度和 1.36×10^-8 M 的检测限，具有实时和原位分析的优势。在存在许多其他金属离子的情况下，它表现出良好的选择性，并为实际基质中的分析提供了潜力，特别是在必须在短时间内分析的环境样品中。这可能为光学定量分析其他小分子的传感平台的制备提供思路，补充现有的工具。
