替格瑞洛超敏反应及氯吡格雷低反应性：一例报告
Hypersensitivity to ticagrelor and low response to clopidogrel: a case report.
作者信息
Dai Jing, Lyu Shuzheng, Ge Changjiang
机构信息
Department of Cardiology, Capital Medical University Affiliated to Beijing Anzhen Hospital, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China.
出版信息
Asia Pac Allergy. 2017 Jan;7(1):51-53. doi: 10.5415/apallergy.2017.7.1.51. Epub 2017 Jan 26.
Abstract
Ticagrelor is widely used to treat acute coronary syndrome. Hypersensitivity reaction of ticagrelor is rarely recognized. A low response to clopidogrel, which occurs in up to 23% of patients, is an independent risk factor for stent thrombosis. Management of patients with a low response to clopidogrel and ticagrelor hypersensitivity who are undergoing antithrombotic therapy remains to be a challenge. Herein, we report a patient with low response to clopidogrel and ticagrelor hypersensitivity, who was successfully managed using aspirin and warfarin.
摘要
替格瑞洛被广泛用于治疗急性冠状动脉综合征。替格瑞洛的超敏反应很少被认识到。氯吡格雷低反应在高达23%的患者中出现，是支架血栓形成的独立危险因素。对于正在接受抗栓治疗的氯吡格雷低反应和替格瑞洛超敏患者的管理仍然是一项挑战。在此，我们报告一名氯吡格雷低反应和替格瑞洛超敏患者，其使用阿司匹林和华法林成功得到管理。
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