Kravtsova N A, Kiniaĭkin M F, Tril' N M, Ivanov E M
Vopr Kurortol Fizioter Lech Fiz Kult. 1989 Jul-Aug(4):21-3.
Consideration is given to time course changes in microcirculatory bed, hemostasis and fibrinolysis in patients with acute NPD and the trend of these changes upon autotransfusion of blood exposed to UV radiation. The doses of the blood varied. It was found that acute phase of the disease is characterized by impairment of hemostasis and fibrinolysis typical for DIC-syndrome. The autotransfusion promoted activation of fibrinolysis, hypocoagulation tendency, reduction of perivascular edema and sludge of red blood cells. Less beneficial effect was observed for the blood dose range of 1.5-2.0 ml/kg manifesting a transitory tendency to hypercoagulation and enhancement of erythrocytic sludge resulting in clinical aggravation in the middle of the treatment course. The highest response occurred in the dose range of 0.7-1.0 ml/kg which is proposed for management of NPD sufferers.
研究了急性非穿透性损伤（NPD）患者微循环床、止血和纤维蛋白溶解的时程变化，以及经紫外线照射的自体输血后这些变化的趋势。血液剂量各不相同。结果发现，疾病急性期的特征是出现弥漫性血管内凝血（DIC）综合征典型的止血和纤维蛋白溶解障碍。自体输血促进了纤维蛋白溶解的激活、低凝倾向、血管周围水肿的减轻和红细胞淤滞。在1.5 - 2.0 ml/kg的血液剂量范围内观察到的有益效果较小，表现为短暂的高凝倾向和红细胞淤滞加重，导致治疗过程中期临床症状加重。最高反应出现在0.7 - 1.0 ml/kg的剂量范围内，该剂量范围建议用于NPD患者的治疗。
