Umiński J, Cisak E, Chmielewska-Badora J, Skomra S
Wiad Parazytol. 1989;35(4):289-97.
In order to detect centres of family toxoplasmosis in rural environment 24,546 patients, suspected of invasion of T. gondii, 504 healthy persons coming from villages and 1,681 live stock were examined. Among persons suspected of infection of T. gondii, 65 cases of congenital family toxoplasmosis and 19 cases of environment family toxoplasmosis, involving several members of the family were detected. In animals a comparatively high percentage with positive reaction in the direct agglutination test (cattle 55.5%, swine 27.9%, sheep 23.4%) was detected. The following serological tests were applied to humans: complement-binding test (OWD), indirect immunofluorescence test (OIF), direct agglutination test with 2-mercaptoethanol (CA), ELISA IgM and, selectively, immunoperoxidase test IgM (OIP). The results suggest that the environment conditions can play an important role in the occurrence of family toxoplasmosis in our country, especially in the countryside. Detecting active toxoplasmosis in a family member should be a signal to start serological-epidemiological examination of the remaining family members and live stock.
为了在农村环境中检测家庭弓形虫病中心，对24546名疑似弓形虫感染的患者、504名来自村庄的健康人和1681头牲畜进行了检查。在疑似弓形虫感染的人群中，检测到65例先天性家庭弓形虫病和19例环境性家庭弓形虫病，涉及多个家庭成员。在动物中，直接凝集试验阳性反应的比例相对较高（牛55.5%，猪27.9%，羊23.4%）。对人类应用了以下血清学检测：补体结合试验（OWD）、间接免疫荧光试验（OIF）、2-巯基乙醇直接凝集试验（CA）、ELISA IgM以及选择性的免疫过氧化物酶试验IgM（OIP）。结果表明，环境条件在我国家庭弓形虫病的发生中可能起重要作用，尤其是在农村地区。检测到一名家庭成员患有活动性弓形虫病应成为对其余家庭成员和牲畜进行血清学-流行病学检查的信号。
