Lin Hung-Che, Chou Yu-Ching, Wang Chih-Hung, Hung Li-Wen, Shih Cheng-Ping, Kang Bor-Hwang, Yeh Wen-Ying, Chen Hsin-Chien
Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
School of Public Health, National Defense Medical Center, Taipei, Taiwan.
Auris Nasus Larynx. 2017 Dec;44(6):678-684. doi: 10.1016/j.anl.2017.01.004. Epub 2017 Jan 31.
To investigate the latency and amplitude of auditory brainstem response (ABR) and hearing prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).
Patients with ISSNHL were classified into four different recovery groups. All patients' clinical and demographic features were analyzed. Two-channel ABRs were collected in response to click stimuli at 90dB nHL. ABR amplitudes for wave I and ABR latency for waves I, III, and V were analyzed.
One hundred and two patients (54 men and 48 women) were included in the study. Hearing recovery was observed in 72 cases (70.6%). Waves I, III, and V latencies were significantly prolonged in the affected ears compared with the unaffected ears. A smaller wave I amplitude was found in the affected ear compared with the unaffected ear in the three recovery groups. There was a significant association between wave I latency and hearing outcome (p=0.009) with a prolonged trend from complete to slight hearing recovery group.
There was a significant correlation between wave I latency and hearing outcome in patients with ISSNHL. The finding may provide diagnostic information and serve as a potential prognostic indicator in patients with ISSNHL.
探讨特发性突发性感音神经性听力损失（ISSNHL）患者的听性脑干反应（ABR）潜伏期和波幅以及听力预后情况。
将ISSNHL患者分为四个不同的恢复组。分析所有患者的临床和人口统计学特征。以90dB nHL的短声刺激采集两通道ABR。分析I波的ABR波幅以及I、III和V波的ABR潜伏期。
102例患者（54例男性和48例女性）纳入研究。72例（70.6%）观察到听力恢复。患耳的I、III和V波潜伏期较健耳显著延长。在三个恢复组中，患耳的I波幅较健耳更小。I波潜伏期与听力结果之间存在显著关联（p=0.009），从完全恢复到轻度恢复组呈延长趋势。
ISSNHL患者的I波潜伏期与听力结果之间存在显著相关性。这一发现可为ISSNHL患者提供诊断信息并作为潜在的预后指标。
