Cossu G, Lacroix C, Adams C, Daniel R T, Parker F, Messerer M
Department of neurosurgery, university hospital of Lausanne, 46, rue du Bugnon, 1010 Lausanne, Switzerland.
Department of neuropathology, Bicêtre hospital, Paris-Sud university, 94270 Paris, France.
Neurochirurgie. 2017 Nov;63(5):413-418. doi: 10.1016/j.neuchi.2016.06.006. Epub 2017 Feb 1.
Intramedullary tumors constitute approximately 5% of spinal tumors and about 80% are of neuroglial origin. We reviewed our series of adult patients with spinal neuroglial intramedullary tumors operated on between 1984 and 2011 at the neurosurgical department of Bicêtre hospital. The histopathological records for 196 patients were retrospectively analyzed. The majority of tumors were ependymomas (68%) and astrocytomas (27.5%). The importance of a proper and detailed neuropathological diagnosis is the key to define patient management. The available literature data about the genetic profiles of these rare tumors are summarized and reviewed.
髓内肿瘤约占脊柱肿瘤的5%，其中约80%起源于神经胶质。我们回顾了1984年至2011年期间在比塞特尔医院神经外科接受手术的成年脊柱神经胶质髓内肿瘤患者系列。对196例患者的组织病理学记录进行了回顾性分析。大多数肿瘤为室管膜瘤（68%）和星形细胞瘤（27.5%）。进行恰当且详细的神经病理学诊断对于确定患者的治疗方案至关重要。本文总结并回顾了关于这些罕见肿瘤基因谱的现有文献数据。
