Paramio A, Fernández-Britto J E
Department of Pathology Hospital of Medicine, "Commandante Manuel Fajardo", Cuba.
Zentralbl Allg Pathol. 1989;135(6):631-5.
A semi-serial histopathological study was conducted into the cardiac conduction system (CCS) of 14 autopsy subjects with dilated idiopathic cardiomyopathy (DIC). Clinical and pathomorphological data corresponding to this disease were compiled by Hudson's criteria. The most important histopathological findings were the frequency of vascular changes observed in small-size arteries that irrigate the sino-atrial and atrioventricular nodes, the bundle of His, the origin of both bundle branches, and the upper portion of the ventricular septum. Vascular changes, although unequal and inconstant, together with regressive and inflammatory features were observed in the majority of specimens. Also, good correlations were found to exist between electrocardiographic data and the direct cause of death, the intensity and/or extension of lesions did not correlate with the duration of the disease. While the vascular lesions might have been the first pathological changes, their variability and inconsistency suggested that more than one aetiological factors were involved in this type of cardiomyopathy.
对14例扩张型特发性心肌病（DIC）尸检对象的心脏传导系统（CCS）进行了半连续组织病理学研究。根据哈德森标准收集了与该疾病相关的临床和病理形态学数据。最重要的组织病理学发现是在为窦房结、房室结、希氏束、双侧束支起源及室间隔上部供血的小动脉中观察到的血管变化频率。在大多数标本中均观察到血管变化，尽管这些变化不均衡且不恒定，同时伴有退行性和炎症特征。此外，还发现心电图数据与直接死因之间存在良好的相关性，而病变的强度和/或范围与疾病持续时间无关。虽然血管病变可能是最初的病理变化，但其变异性和不一致性表明，这类心肌病涉及不止一种病因。
