Peñasco Y, González-Castro A, Rodríguez-Borregán J C, Llorca J
Departamento de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, España.
Departamento de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, España.
Rev Esp Anestesiol Reanim. 2017 May;64(5):250-256. doi: 10.1016/j.redar.2016.11.007. Epub 2017 Feb 3.
To determine the usefulness of the determination of base excess in a cohort of elderly patients admitted to an intensive care unit (ICU) with a diagnosis of chest trauma.
Two hundred and forty-nine patients were included aged 65 years and over with a diagnosis of thoracic trauma who required admission to the ICU. We made a statistical analysis in order to determine the association of the first base excess levels with mortality during the unit stay.
Two hundred and forty-nine patients, with a mean APACHE II score of 16.21±7.87 and 24.45±14.16 ISS. Mean ICU stay was 12.74±16.85 days and the mean hospital stay was 26.55±30.1 days. Statistical analysis showed an association with mortality in patients whose blood pressure was lower than 110mmHg on admission, with an OR=4.11 (95% CI 1.91 to 8.85) compared to patients with blood pressure between 110 and 140mmHg. Those patients who had base excess levels on admission of less than -6mmol/L also showed increased mortality compared to patients with higher levels, with an OR=3.12 (95% CI 1.51 to 6.42).
The presence of a base excess level of less than -6 is associated with increased mortality in elderly patients with initial blood pressure between 110 and 140mmHg, diagnosed with thoracic trauma and who require admission to ICU. Routine measurement of this parameter in this population may show the clinical usefulness of assessing possible hidden hypoperfusion.
确定测定碱剩余在一群因胸部创伤诊断而入住重症监护病房(ICU)的老年患者中的作用。
纳入249例年龄65岁及以上、诊断为胸部创伤且需要入住ICU的患者。我们进行了统计分析,以确定最初的碱剩余水平与在ICU住院期间死亡率之间的关联。
249例患者,平均急性生理学与慢性健康状况评分系统(APACHE II)评分为16.21±7.87,损伤严重度评分(ISS)为24.45±14.16。平均ICU住院时间为12.74±16.85天,平均住院时间为26.55±30.1天。统计分析显示,入院时血压低于110mmHg的患者与死亡率有关联,与血压在110至140mmHg之间的患者相比,比值比(OR)=4.11(95%置信区间1.91至8.85)。入院时碱剩余水平低于-6mmol/L的患者与碱剩余水平较高的患者相比,死亡率也有所增加,OR=3.12(95%置信区间1.51至6.42)。
对于初始血压在110至140mmHg之间、诊断为胸部创伤且需要入住ICU的老年患者,碱剩余水平低于-6与死亡率增加有关。在这一人群中常规测量该参数可能显示出评估潜在隐匿性低灌注的临床作用。