Jiménez-Sánchez Alfonso
Dpto. Genética, Universidad de Extremadura, E06071 Badajoz, Spain.
J Theor Biol. 2017 Apr 21;419:8-12. doi: 10.1016/j.jtbi.2017.01.045. Epub 2017 Feb 2.
A proposal is presented for classifying bacterial cell cycles into twelve discrete groups. This classification translates the three temporal parameters that define a cell cycle into numbers that facilitate an algorithmic approach to analyse the replication state of a single bacterium and of a bacterial population during steady-state of exponential growth. The classification and its implementation offer easy ways to obtain the rate of DNA synthesis and the amount of DNA per cell at any age in batch cultures.
本文提出了一种将细菌细胞周期分为十二个离散组的方案。这种分类将定义细胞周期的三个时间参数转化为数字,便于采用算法方法分析单个细菌以及处于指数生长稳态的细菌群体的复制状态。该分类及其实施提供了简便方法,可用于获取分批培养中任何时期的DNA合成速率和每个细胞的DNA量。