Ding J, Hashimoto H, Tsuneyoshi M, Enjoji M, Masuda S, Ushijima M
Second Department of Pathology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Acta Pathol Jpn. 1989 Aug;39(8):533-8. doi: 10.1111/j.1440-1827.1989.tb01520.x.
A case of clear cell chondrosarcoma located in the right proximal end of the femur is presented. Radiologically, the tumor appeared as a large osteolytic lesion with mottled calcification resembling chondroblastoma. Histologically, the greater portion was made up of tumor cells with abundant clear cytoplasm and usually distinct boundaries, associated with areas of conventional chondrosarcoma. The proportion of the clear cell areas was about 60%, and they were mainly distributed along the tumor periphery. Moreover, myxoid chondrosarcoma-like areas, a feature not previously mentioned in clear cell chondrosarcoma, were observed, occupying about 10% of the tumor area.
本文报告一例位于右股骨近端的透明细胞软骨肉瘤。影像学上，肿瘤表现为一个大的溶骨性病变，伴有斑点状钙化，类似软骨母细胞瘤。组织学上，大部分由具有丰富透明细胞质且边界通常清晰的肿瘤细胞组成，并伴有传统型软骨肉瘤区域。透明细胞区域的比例约为60%，主要沿肿瘤周边分布。此外，还观察到黏液样软骨肉瘤样区域，这是透明细胞软骨肉瘤之前未提及的特征，占肿瘤面积的约10%。
