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Special issue: "MET as actionable target in cancer therapy".

作者信息

Ma Patrick C

机构信息

WVU Cancer Institute, West Virginia University, Morgantown, WV 26505, USA;; West Virginia Clinical and Translational Science Institute, Morgantown, WV 26505, USA.

出版信息

Ann Transl Med. 2017 Jan;5(1):1. doi: 10.21037/atm.2017.01.10.

DOI:10.21037/atm.2017.01.10
PMID:28164086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5253282/
Abstract
摘要

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Cancer Discov. 2015 Aug;5(8):802-5. doi: 10.1158/2159-8290.CD-15-0769.
2
Next-Generation Sequencing of Pulmonary Sarcomatoid Carcinoma Reveals High Frequency of Actionable MET Gene Mutations.肺肉瘤样癌的下一代测序揭示了 MET 基因高频激活突变。
J Clin Oncol. 2016 Mar 10;34(8):794-802. doi: 10.1200/JCO.2015.62.0674. Epub 2015 Jul 27.
3
Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping.携带导致第14外显子跳跃的MET突变的IV期肺腺癌患者对MET抑制剂的反应。
Cancer Discov. 2015 Aug;5(8):842-9. doi: 10.1158/2159-8290.CD-14-1467. Epub 2015 May 13.
4
Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors.MET 基因通过不同的外显子 14 剪接改变而被激活,这种改变发生在多种肿瘤类型中,并赋予了对 MET 抑制剂的临床敏感性。
Cancer Discov. 2015 Aug;5(8):850-9. doi: 10.1158/2159-8290.CD-15-0285. Epub 2015 May 13.
5
Comprehensive molecular profiling of lung adenocarcinoma.肺腺癌的全面分子分析。
Nature. 2014 Jul 31;511(7511):543-50. doi: 10.1038/nature13385. Epub 2014 Jul 9.
6
Mechanisms of Resistance to Epidermal Growth Factor Receptor Inhibitors and Novel Therapeutic Strategies to Overcome Resistance in NSCLC Patients.非小细胞肺癌患者对表皮生长因子受体抑制剂的耐药机制及克服耐药的新型治疗策略
Chemother Res Pract. 2012;2012:817297. doi: 10.1155/2012/817297. Epub 2012 Aug 29.
7
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Cell. 2011 Mar 4;144(5):646-74. doi: 10.1016/j.cell.2011.02.013.