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威胁下的抑制控制:自发性眨眼在创伤后应激障碍中的作用。

Inhibitory Control under Threat: The Role of Spontaneous Eye Blinks in Post-Traumatic Stress Disorder.

作者信息

Rubin Mikael, Hien Denise A, Das Dipanjana, Melara Robert D

机构信息

Department of Psychology, City College, City University of New York, New York, NY 10017, USA.

Department of Psychology, University of Texas at Austin, Austin, TX 78705, USA.

出版信息

Brain Sci. 2017 Feb 4;7(2):16. doi: 10.3390/brainsci7020016.

Abstract

This study is the first to explore spontaneous eye blink rate (sEBR) in individuals with post-traumatic stress disorder (PTSD). We investigated the connection between the magnitude of flanker interference in PTSD participants and sEBR during performance on a modified version of the Eriksen flanker task. As a peripheral measure of cognitive control and dopaminergic function, sEBR may illuminate the relationship between PTSD and executive function. Findings revealed a positive relationship between sEBR and flanker interference in participants diagnosed with PTSD, to both threat-related and neutral stimuli, whereas this relationship was negative in participants exposed to trauma but without PTSD and in healthy controls. Although our results are suggestive of sEBR as a potential physiological index of emotional management in PTSD, most of the correlations were not significant, indicating that further research with a larger sample is needed.

摘要

本研究首次探讨创伤后应激障碍(PTSD)患者的自发眨眼率(sEBR)。我们在一项改良版的埃里克森侧翼任务中,调查了PTSD参与者侧翼干扰的程度与sEBR之间的联系。作为认知控制和多巴胺能功能的外周指标,sEBR可能有助于阐明PTSD与执行功能之间的关系。研究结果显示,被诊断为PTSD的参与者在面对与威胁相关和中性刺激时,sEBR与侧翼干扰呈正相关,而在遭受创伤但未患PTSD的参与者和健康对照组中,这种关系呈负相关。虽然我们的结果表明sEBR可能是PTSD情绪管理的潜在生理指标,但大多数相关性并不显著,这表明需要对更大样本进行进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba9c/5332959/614b733a7ad5/brainsci-07-00016-g001.jpg

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