Das A, Pandit S, Das S K, Basuthakur S, Das S
Department of Pulmonary Medicine, Medical College, Kolkata, West Bengal, India.
Kathmandu Univ Med J (KUMJ). 2016 Apr-Jun;14(54):177-180.
Pulmonary involvement by Aspergillus sp. mainly includes allergic bronchopulmonary aspergillosis, aspergilloma, and invasive aspergillosis. Aspergilloma (Fungal ball) is the most common form of aspergillous pulmonary involvement, which occurs in preexisting pulmonary cavities, especially secondary to pulmonary tuberculosis. Ankylosing spondylitis is a rare cause of upper lobe fibro-cavitary lesions in pulmonary parenchyma. It may also lead to development of fungal balls in pulmonary cavities. Most common presentation is mild to massive hemoptysis; dyspnoea, chronic cough, expectoration may be other presentation; even the patient may remain asymptomatic. Intaracavitary mobile mass is a valuable sign for fungal ball, best detected by computed tomography (CT) scan of thorax. Lobectomy is the treatment of choice to stop the hemoptysis, if the general condition of the patient is fit; otherwise associated co-morbidities complicate the post-operative scenario. In this situation, bronchial artery embolization may be used as a temporary measure to control hemoptysis. Here, we report a case of bilateral aspergillomas within the cavities located in upper lobes of both lungs in a 74 years old male who was suffering from ankylosing spondylitis for last 42 years.
曲霉菌属对肺部的累及主要包括变应性支气管肺曲霉菌病、曲菌球和侵袭性曲霉菌病。曲菌球是曲霉菌肺部累及最常见的形式,发生于既往存在的肺空洞内,尤其是继发于肺结核之后。强直性脊柱炎是肺实质中上叶纤维空洞性病变的罕见病因。它也可能导致肺空洞内曲菌球的形成。最常见的表现是轻度至大量咯血;呼吸困难、慢性咳嗽、咳痰可能是其他表现;甚至患者可能无症状。空洞内可移动团块是曲菌球的一个重要征象,通过胸部计算机断层扫描(CT)最易检测到。如果患者一般状况良好,肺叶切除术是止血的首选治疗方法;否则,相关的合并症会使术后情况复杂化。在这种情况下,支气管动脉栓塞可作为控制咯血的临时措施。在此,我们报告一例74岁男性患者,其双肺上叶空洞内有双侧曲菌球,该患者患有强直性脊柱炎已达42年。