Wehring Heidi J, Heishman Stephen J, McMahon Robert P, Liu Fang, Feldman Stephanie, Raley Heather, Weiner Elaine, Kelly Deanna L
a Maryland Psychiatric Research Center, University of Maryland School of Medicine , Baltimore , MD , USA.
b National Institute of Health, National Institute on Drug Abuse, Intramural Research Program , Baltimore , MD , USA.
J Dual Diagn. 2017 Jan-Mar;13(1):36-42. doi: 10.1080/15504263.2017.1288946.
Nicotine dependence is high in schizophrenia, and craving is known to impact relapse during quit attempts.
We compared tobacco craving in smokers with schizophrenia treated with different antipsychotics.
Mean craving scores were lowest in participants receiving first-generation antipsychotics, although these differences were not statistically significant. Craving with clozapine was not lower than with other antipsychotics.
Further research is needed to determine whether differences in craving exist between antipsychotic classes.
精神分裂症患者的尼古丁依赖程度较高，且已知在戒烟尝试期间，渴求会影响复发情况。
我们比较了使用不同抗精神病药物治疗的精神分裂症吸烟者的烟草渴求情况。
接受第一代抗精神病药物治疗的参与者的平均渴求得分最低，不过这些差异无统计学意义。氯氮平治疗时的渴求程度并不低于其他抗精神病药物。
需要进一步研究以确定不同类别抗精神病药物之间在渴求方面是否存在差异。
