精神分裂症患者的抗精神病药物治疗与烟草渴望
Antipsychotic Treatment and Tobacco Craving in People With Schizophrenia.
作者信息
Wehring Heidi J, Heishman Stephen J, McMahon Robert P, Liu Fang, Feldman Stephanie, Raley Heather, Weiner Elaine, Kelly Deanna L
机构信息
a Maryland Psychiatric Research Center, University of Maryland School of Medicine , Baltimore , MD , USA.
b National Institute of Health, National Institute on Drug Abuse, Intramural Research Program , Baltimore , MD , USA.
出版信息
J Dual Diagn. 2017 Jan-Mar;13(1):36-42. doi: 10.1080/15504263.2017.1288946.
Abstract
OBJECTIVE
Nicotine dependence is high in schizophrenia, and craving is known to impact relapse during quit attempts.
METHODS
We compared tobacco craving in smokers with schizophrenia treated with different antipsychotics.
RESULTS
Mean craving scores were lowest in participants receiving first-generation antipsychotics, although these differences were not statistically significant. Craving with clozapine was not lower than with other antipsychotics.
CONCLUSIONS
Further research is needed to determine whether differences in craving exist between antipsychotic classes.
摘要
目的
精神分裂症患者的尼古丁依赖程度较高，且已知在戒烟尝试期间，渴求会影响复发情况。
方法
我们比较了使用不同抗精神病药物治疗的精神分裂症吸烟者的烟草渴求情况。
结果
接受第一代抗精神病药物治疗的参与者的平均渴求得分最低，不过这些差异无统计学意义。氯氮平治疗时的渴求程度并不低于其他抗精神病药物。
结论
需要进一步研究以确定不同类别抗精神病药物之间在渴求方面是否存在差异。
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