Cai Congbo, Zeng Yiqing, Zhuang Yuchuan, Cai Shuhui, Chen Lin, Ding Xinghao, Bao Lijun, Zhong Jianhui, Chen Zhong
IEEE Trans Biomed Eng. 2017 Oct;64(10):2450-2461. doi: 10.1109/TBME.2017.2661840. Epub 2017 Jan 31.
Develop a reliable single-shot T mapping method with extra robustness to motion and the potential for real-time dynamic and quantitative MR imaging.
A single-shot T mapping sequence was proposed based on spin-echo planar imaging acquisition scheme. Two overlapped echo signals with different T weighting were obtained simultaneously by using two small flip-angle excitation pulses and corresponding echo-shifting gradients. A detachment algorithm based on structure similarity constraint was proposed to separate the two echo signals. T mapping was obtained from the two separated echo signals.
The robustness and efficiency of the method were demonstrated through simulation, phantom experiments, and human brain measurements.
Reliable T mapping can be obtained within milliseconds even under continuous head motion.
Reliable T mapping was achieved with a single shot for the first time. The proposed method will facilitate real-time dynamic and quantitative MR imaging.
开发一种可靠的单次T映射方法,该方法对运动具有更高的鲁棒性,并具有实时动态和定量磁共振成像的潜力。
基于自旋回波平面成像采集方案提出了一种单次T映射序列。通过使用两个小翻转角激发脉冲和相应的回波移位梯度,同时获得具有不同T加权的两个重叠回波信号。提出了一种基于结构相似性约束的分离算法来分离这两个回波信号。从两个分离的回波信号中获得T映射。
通过模拟、体模实验和人脑测量证明了该方法的鲁棒性和效率。
即使在头部连续运动的情况下,也能在几毫秒内获得可靠的T映射。
首次实现了单次可靠的T映射。所提出的方法将有助于实时动态和定量磁共振成像。