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通过重叠回波分离(OLED)平面成像实现单次 ${\text{T}}_{{2}}$ 映射

Single-Shot ${\text{T}}_{{2}}$ Mapping Through OverLapping-Echo Detachment (OLED) Planar Imaging.

作者信息

Cai Congbo, Zeng Yiqing, Zhuang Yuchuan, Cai Shuhui, Chen Lin, Ding Xinghao, Bao Lijun, Zhong Jianhui, Chen Zhong

出版信息

IEEE Trans Biomed Eng. 2017 Oct;64(10):2450-2461. doi: 10.1109/TBME.2017.2661840. Epub 2017 Jan 31.

Abstract

OBJECTIVE

Develop a reliable single-shot T mapping method with extra robustness to motion and the potential for real-time dynamic and quantitative MR imaging.

METHODS

A single-shot T mapping sequence was proposed based on spin-echo planar imaging acquisition scheme. Two overlapped echo signals with different T weighting were obtained simultaneously by using two small flip-angle excitation pulses and corresponding echo-shifting gradients. A detachment algorithm based on structure similarity constraint was proposed to separate the two echo signals. T mapping was obtained from the two separated echo signals.

RESULTS

The robustness and efficiency of the method were demonstrated through simulation, phantom experiments, and human brain measurements.

CONCLUSION

Reliable T mapping can be obtained within milliseconds even under continuous head motion.

SIGNIFICANCE

Reliable T mapping was achieved with a single shot for the first time. The proposed method will facilitate real-time dynamic and quantitative MR imaging.

摘要

目的

开发一种可靠的单次T映射方法,该方法对运动具有更高的鲁棒性,并具有实时动态和定量磁共振成像的潜力。

方法

基于自旋回波平面成像采集方案提出了一种单次T映射序列。通过使用两个小翻转角激发脉冲和相应的回波移位梯度,同时获得具有不同T加权的两个重叠回波信号。提出了一种基于结构相似性约束的分离算法来分离这两个回波信号。从两个分离的回波信号中获得T映射。

结果

通过模拟、体模实验和人脑测量证明了该方法的鲁棒性和效率。

结论

即使在头部连续运动的情况下,也能在几毫秒内获得可靠的T映射。

意义

首次实现了单次可靠的T映射。所提出的方法将有助于实时动态和定量磁共振成像。

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