Nokhodian Zary, Ataei Behrooz, Moradi Abdolreza, Yaran Majid, Hoseini Shervin Gaffari, Feizi Awat, Sherkat Roya
Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Isfahan Veterinary Office, Head of Public Health Supervision Section, Isfahan, Iran.
Acta Trop. 2017 May;169:107-111. doi: 10.1016/j.actatropica.2017.02.002. Epub 2017 Feb 5.
In order to evaluate the prevalence of antibodies against phase I and II antigens of Coxiella Burnetii and to identify related risk factors among high-risk groups in the center of Iran, a serological survey was performed in Isfahan County. In a cross-sectional study, 401 sera were collected from slaughterhouse workers, butchers, farmers and veterinarians in spring 2015. Samples were tested for specific immunoglobulin G (IgG) antibodies against phase I and II of C. burnetii by indirect immunofluorescence assay. A checklist was fulfilled to document demographic information. Univariate analysis and multivariable binary logistic regression model were used to analyze data. IgG antibodies against phases I and II of C. burnetii were detected in 19% and 36.9% of participants, respectively. The overall seropositivity (IgG against phase I and/or II) was 43.1%. The present study shows a high seroprevalence of C. burnetii infection among high-risk population in center of Iran. It is suggested to carry out occupational health monitoring programs for individuals who may be exposed to C. burnetii.
为了评估伊朗中部高危人群中针对伯纳特柯克斯体I期和II期抗原的抗体流行情况，并确定相关风险因素，在伊斯法罕县进行了一项血清学调查。在一项横断面研究中，于2015年春季从屠宰场工人、屠夫、农民和兽医中收集了401份血清样本。通过间接免疫荧光法检测样本中针对伯纳特柯克斯体I期和II期的特异性免疫球蛋白G（IgG）抗体。完成了一份清单以记录人口统计学信息。采用单因素分析和多变量二元逻辑回归模型分析数据。分别在19%和36.9%的参与者中检测到针对伯纳特柯克斯体I期和II期的IgG抗体。总体血清阳性率（针对I期和/或II期的IgG）为43.1%。本研究表明伊朗中部高危人群中伯纳特柯克斯体感染的血清流行率较高。建议对可能接触伯纳特柯克斯体的个体开展职业健康监测项目。
