R Sharma I P Cast C O'Brien R
a Departments of Surgical Neurology and Pathology, Morriston Hospital, Morriston, Swansea SA66NL, Wales.
Br J Neurosurg. 1995;9(1):81-84. doi: 10.1080/02688699550041809.
Solitary or multiple supratentorial haemangioblastomas are rare and may be associated with Von Hippel-Lindau complex (VHLC), polycythaemia or a family history of VHLC. An extensive review of the literature (1902-1992) has revealed 112 cases. They account for 2-8% of all haemangioblastomas and are commonly intraparenchymatous (86.8%) and infrequently intraventricular (6.6%). However, a meningeal location (5.6%) is extremely rare. Only one case of a solitary leptomeningeal haemangioblastoma has previously been reported and this was associated with a family and personal history of VHLC, cerebellar haemangioblastomas and renal carcinoma. We report a solitary solid left parietal leptomeningeal haemangioblastoma mimicking a meningioma or a secondary deposit on computed tomography in a 72-year-old male. There were no manifestations of or a family history of VHLC or polycythaemia.
孤立性或多发性幕上血管母细胞瘤较为罕见，可能与冯·希佩尔－林道综合征（VHLC）、红细胞增多症或VHLC家族史相关。对1902年至1992年的文献进行全面回顾后发现了112例病例。它们占所有血管母细胞瘤的2%至8%，通常位于脑实质内（86.8%），位于脑室内的情况较少见（6.6%）。然而，位于脑膜的情况（5.6%）极为罕见。此前仅报道过1例孤立性软脑膜血管母细胞瘤病例，该病例与VHLC家族史及个人史、小脑血管母细胞瘤和肾癌有关。我们报告1例72岁男性患者，其孤立性实性左顶叶软脑膜血管母细胞瘤在计算机断层扫描上酷似脑膜瘤或转移瘤。该患者无VHLC或红细胞增多症的表现及家族史。
