Hsiao C C, Chiou S S, Hsu H-T, Lin P C, Liao Y M, Wu L-M
Division of Hematology/Oncology, Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Division of Hematology/Oncology, Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Eur J Cancer Care (Engl). 2018 Nov;27(6):e12661. doi: 10.1111/ecc.12661. Epub 2017 Feb 7.
Advanced therapies have improved outcomes and also resulted in a growing risk of long-term adverse health events. This study intends to estimate incidences of adverse health events and examine differences in adverse health events among childhood cancer survivors, and to understand the concerns of mothers after their child has completed cancer treatment. An explanatory sequential mixed-method was used. A total of 201 paediatric cancer survivors' mothers with mean age 43.6 years were recruited. Of the survivors, 12.4% experienced five or more adverse health events. The incidence of adverse health events of altered body image, fatigue and neurocognitive problems were 31.54%, 14.77% and 12.53% respectively. Among survivors, significant differences in adverse health events of pain, endocrine problems and altered body image issues were identified. Survivors receiving radiotherapy, bone marrow transplants or completing treatment after 6-10 years experienced significantly more adverse health events. Maintaining health was the greatest concern for mothers, and the qualitative reports of their concerns could be categorised: living in uncertainty, and keeping forward-looking. Childhood brain tumour survivors were identified as experiencing more adverse health events than other survivors. The need for healthcare teams to consider mothers' health concerns was highlighted.
先进疗法改善了治疗效果，但也导致长期不良健康事件的风险不断增加。本研究旨在估计不良健康事件的发生率，检查儿童癌症幸存者中不良健康事件的差异，并了解孩子完成癌症治疗后母亲们的担忧。采用了解释性顺序混合方法。共招募了201名平均年龄为43.6岁的儿科癌症幸存者的母亲。在幸存者中，12.4%经历了五次或更多的不良健康事件。身体形象改变、疲劳和神经认知问题的不良健康事件发生率分别为31.54%、14.77%和12.53%。在幸存者中，疼痛、内分泌问题和身体形象改变问题的不良健康事件存在显著差异。接受放疗、骨髓移植或在6至10年后完成治疗的幸存者经历的不良健康事件明显更多。保持健康是母亲们最关心的问题，她们担忧的定性报告可分为：生活在不确定性中，以及保持前瞻性。儿童脑肿瘤幸存者被确定比其他幸存者经历更多的不良健康事件。强调了医疗团队考虑母亲健康担忧的必要性。
